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Esther Kristiningrum
Medical Department, PT Kalbe Farma Tbk., Jakarta, Indonesia
Health Professions Medicine & Pharmacology Public Health

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Terapi Post-dural Puncture Headache Esther Kristiningrum
Cermin Dunia Kedokteran Vol 41, No 12 (2014): Endokrin
Publisher : PT. Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v41i12.1062

Abstract

Nyeri kepala pasca-pungsi dura / Post-dural Puncture Headcahe (PDPH) merupakan salah satu komplikasi yang paling sering dari pungsi lumbal diagnostik, terapeutik, atau yang tidak disengaja. Dokter yang melakukan prosedur ini harus mengenal dengan baik strategi pencegahan dan terapi PDPH. Terapi PDPH meliputi penatalaksanaan konservatif, penatalaksanaan medis agresif, terapi invasif konvensional, dan terapi invasif agresif.Post-dural puncture headache (PDPH) is one of the most common complications of diagnostic, therapeutic or inadvertent lumbar punctures. Clinicians who perform these procedures should be familiar with strategies for preventing and treatment of PDPH. The therapeutic approach to PDPH includes conservative management, aggressive medical management, conventional invasive treatments, and aggressive invasive treatments. 
Penggunaan Obat Pelumpuh Otot di ICU Esther Kristiningrum
Cermin Dunia Kedokteran Vol 42, No 10 (2015): Neurologi
Publisher : PT. Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v42i10.962

Abstract

Obat pelumpuh otot melumpuhkan/merelaksasi otot rangka dengan menghambat transmisi impuls saraf pada sambungan otot-saraf. Obat pelumpuh otot dibagi menjadi obat depolarisasi dan non-depolarisasi. Obat ini dapat bermanfaat di unit perawatan intensif (ICU) untuk berbagai kondisi klinik. Dokter sebaiknya memilih suatu obat pelumpuh otot berdasarkan farmakologi obat dan karakteristik individu. Monitoring klinis dan train-of-four (TOF) direkomendasikan untuk menurunkan risiko komplikasi terkait dengan obat pelumpuh otot.Neuromuscular blocking agents (NMBAs) paralyze skeletal muscles by blocking nerve impulses at myoneural junction. It is categorized into depolarizing or nondepolarizing agents based upon their mechanism of action. These drugs may be useful in the intensive care unit (ICU) for a variety of clinical conditions. The clinician should choose an NMBA on the basis of drug pharmacology and individual characteristics. Both clinical and train-of-four (TOF) monitoring was recommended to reduce risk of complication associated with NMBA.
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