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Erlinda Karyadi
Faculty of Medicine, Maranatha Christian University, Bandung, Indonesia
Health Professions Medicine & Pharmacology Public Health

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Cutaneous Mucormycosis Erlinda Karyadi; Leoni Agnes
Cermin Dunia Kedokteran Vol 49, No 2 (2022): Infeksi
Publisher : PT. Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v49i2.1740

Abstract

Cutaneous mucormycosis is an emerging fungal infection caused by opportunistic fungi from phylum Glomeromycota. This disease is frequently found in poorly controlled diabetic patients and immunosuppressed individuals. It is usually acquired by direct inoculation through trauma.The clinical presentation is nonspecific indurated plaque rapidly evolves to necrosis. Diagnosis should be confirmed by demonstration of the etiological agent and molecular tests. First-line therapy is amphotericin B combined with surgery; second line treatment include posaconazoleand isavuconazole. Cutaneous mucormycosis adalah infeksi jamur oportunistik dari filum Glomerycota. Penyakit ini sering dijumpai pada pasien diabetes tidak terkontrol serta pada pasien imunosupresi. Penyebaran penyakit ini umumnya inokulasi langsung melalui trauma. Gambaran klinis berupa plak berindurasi nonspesifik yang berkembang cepat menjadi nekrosis. Diagnosis melalui pemeriksaan kultur dan sejumlah tes molekular. Terapi lini pertama yaitu amphotericin B dengan pembedahan, lini kedua dapat menggunakan posaconazole dan isavuconazole.
Cutaneous Mucormycosis Erlinda Karyadi; Leoni Agnes
Cermin Dunia Kedokteran Vol 49 No 2 (2022): Infeksi
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v49i2.193

Abstract

Cutaneous mucormycosis is an emerging fungal infection caused by opportunistic fungi from phylum Glomeromycota. This disease is frequently found in poorly controlled diabetic patients and immunosuppressed individuals. It is usually acquired by direct inoculation through trauma. The clinical presentation is nonspecific indurated plaque rapidly evolves to necrosis. Diagnosis should be confirmed by demonstration of the etiological agent and molecular tests. First-line therapy is amphotericin B combined with surgery; second line treatment include posaconazole and isavuconazole. Cutaneous mucormycosis adalah infeksi jamur oportunistik dari filum Glomerycota. Penyakit ini sering dijumpai pada pasien diabetes tidak terkontrol serta pada pasien imunosupresi. Penyebaran penyakit ini umumnya inokulasi langsung melalui trauma. Gambaran klinis berupa plak berindurasi nonspesifik yang berkembang cepat menjadi nekrosis. Diagnosis melalui pemeriksaan kultur dan sejumlah tes molekular. Terapi lini pertama yaitu amphotericin B dengan pembedahan, lini kedua dapat menggunakan posaconazole dan isavuconazole.
Cutaneous Mucormycosis Erlinda Karyadi; Leoni Agnes
Cermin Dunia Kedokteran Vol 49 No 2 (2022): Infeksi
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v49i2.193

Abstract

Cutaneous mucormycosis is an emerging fungal infection caused by opportunistic fungi from phylum Glomeromycota. This disease is frequently found in poorly controlled diabetic patients and immunosuppressed individuals. It is usually acquired by direct inoculation through trauma. The clinical presentation is nonspecific indurated plaque rapidly evolves to necrosis. Diagnosis should be confirmed by demonstration of the etiological agent and molecular tests. First-line therapy is amphotericin B combined with surgery; second line treatment include posaconazole and isavuconazole. Cutaneous mucormycosis adalah infeksi jamur oportunistik dari filum Glomerycota. Penyakit ini sering dijumpai pada pasien diabetes tidak terkontrol serta pada pasien imunosupresi. Penyebaran penyakit ini umumnya inokulasi langsung melalui trauma. Gambaran klinis berupa plak berindurasi nonspesifik yang berkembang cepat menjadi nekrosis. Diagnosis melalui pemeriksaan kultur dan sejumlah tes molekular. Terapi lini pertama yaitu amphotericin B dengan pembedahan, lini kedua dapat menggunakan posaconazole dan isavuconazole.
Co-Authors Leoni Agnes