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Riska Puspasari
Peserta PPDS I Neurologi, Fakultas Kedokteran Universitas Airlangga/RSUD Dr. Soetomo Surabaya, Indonesia
Health Professions Medicine & Pharmacology Public Health

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Peran Diabetes Mellitus pada Gejala Klinis Osteoartritis Lutut Riska Puspasari; Hanik Badriyah Hidayati
Cermin Dunia Kedokteran Vol 47, No 4 (2020): Arthritis
Publisher : PT. Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v47i4.386

Abstract

OA adalah penyakit sendi degeneratif kronik progresif yang umum dan menyebabkan gangguan mobilitas sendi sehingga membatasi aktivitas sehari-hari. Hiperglikemia kronik pada DM diduga dapat meningkatkan peradangan sendi dan degradasi kartilago yang meningkatkan risiko kejadian OA dan progresivitasnya. Hasil observasi pada pasien OA lutut di unit rawat jalan saraf RSUD Dr Soetomo Surabaya menunjukkan pasien OA lutut dengan intensitas berat lebih banyak pada penderita DM.Osteoarthritis (OA) of the knee is a common degenerative joint disease which limits daily activities. Many studies suggest a significant relationship between diabetes mellitus (DM) and OA. Chronic hyperglycemia in DM is suspected to increase joint inflammation and cartilage degradation which increases the risk of OA events and their progression. Observations in the neurological outpatient unit of Dr Soetomo Public Hospital Surabaya showed that worse knee OA were more likely to develop among DM patients.
Co-Authors Hanik Badriyah Hidayati,* Mohammad Hasan Machfoed,* Kuntoro,** Soetojo,*** Budi Santoso,**** Suroto,***** Budi Utomo******