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All Journal Proceeding of Mulawarman Pharmaceuticals Conferences
Deva Ayudhia Septiani
Laboratorium Penelitian dan Pengembangan Kefarmasian ?Farmaka Tropis? Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia
Biochemistry, Genetics & Molecular Biology Chemistry Health Professions Immunology & microbiology Medicine & Pharmacology

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Aktivitas Antibakteri Ekstrak Daun Lintut (Hemigraphis sp) Terhadap Bakteri Eschericia coli, Staphylococcus aureus, Staphylococcus epidermidis, dan Salmonella typhi: Antibacterial Activities of Lintut Leaves (Hemigraphis sp) Extract Against Escherichia coli, Staphylococcus aureus, Staphylococcus epidermidis, and Salmonella typhi Bacteria?s Deva Ayudhia Septiani; Wisnu Cahyo Prabowo; Rolan Rusli
Proceeding of Mulawarman Pharmaceuticals Conferences Vol. 13 (2021): Proc. Mul. Pharm. Conf.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (309.438 KB) | DOI: 10.25026/mpc.v13i1.444

Abstract

Lintut plants are herbaceous plants that can grow in soft or watery soil. Research on leaf extracts against Escherichia coli, Staphylococcus aureus, Staphylococcus epidermidis and Salmonella typhi has never been done. This study aims to determine the antibacterial activity of leaf extract against Escherichia coli, Staphylococcus aureus, Staphylococcus epidermidis and Salmonella typhi. The research stages began with the manufacture of simplicia, the manufacture of ethanol extract of lintut leaves, the ethanol extract phytochemical screening test, and the antibacterial activity test using the well diffusion method. The study was conducted using 3 groups of concentrations of lintut leaf extract, namely 7%, 9% and 10% with ampicillin 0.1% as a positive control and aquadest as a negative control. The results of the phytochemical screening test showed that the leaf extract positively contained triterpenoids / steroids and tannins. Antibacterial activity using the well diffusion method showed that the extracts of lintut leaves with a concentration of 7%, 9% and 10% were not significantly different. The best concentration in inhibiting the growth of Escherichia coli, Staphylococcus aureus, Staphylococcus epidermidis and Salmonella typhi was at a concentration of 7%. The positive control used, namely ampicillin, produced a larger diameter of the inhibition zone compared to the diameter of the extract inhibition zone.
Co-Authors Rolan Rusli Wisnu Cahyo Prabowo