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Agus Prastowo
RSUD Prof. Dr. Margono Soekarjo Purwokerto
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Kadar C-Reactive Protein dan Laju Filtrasi Glomerulus Pasien Diabetes Melitus Tipe 2 Obesitas di RSUD Margono Soekarjo Purwokerto Pugud Samodro; Hernayanti Hernayanti; Gesa Gestana A; Agus Prastowo
JURNAL NUTRISIA Vol 18 No 2 (2016): September 2016
Publisher : Poltekkes Kemenkes Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (404.182 KB) | DOI: 10.29238/jnutri.v18i2.59

Abstract

Background. C-Reactive Protein, which is an acute protein as an inflammation marker, is elevated in Type 2 Diabetes Mellitus (T2DM) with obesity. One of the complications of T2DM is diabetic nephropathy, which the kidney disorder occurs due to the atherosclerosis that would cause renal vasoconstriction and decreased Glomerula Filtration Rate (GFR). Objectives. To analyze the correlation of CRP level with GFR in patients with T2DM and obesity in RSUD Margono Soekarjo Purwokerto. Methods. The design of this study is observational analytic with cross sectional approach, carried out on 48 patients T2DM with obesity in Internal Clinic RSUD Margono Soekarjo, aged 35-60 years old. Subjects who use Insulin therapy, antibiotics, anti-inflammatory and diuretic medications, which suffer from kidney disease, liver disease, infection , trauma and dehydration were excluded from the study. Data were analyzed with the Pearson correlation test. Where p < 0,05 indicates a significant correlation. CRP levels were tested with hs-CRP test and GFR calculate with the MDRD formula. Results. Results of the analysis with the Pearson correlation test between CRP levels and GFR values obtained p = 0,045 and r = -0,290. There is a significant correlation between CRP levels and GFR, with negative and moderate correlational strength. Conclusion. There is a correlation between CRP levels and GFR in patients with Type 2 Diabetes and obesity in RSUD Margono Soekarjo Purwokerto. Keywords : C-Reactive Protein (CRP), high sensitivity C-Reactive Protein (hsCRP), Glomerular Filtration Rate (GFR), Type 2 Diabetes with Obesity.
Hubungan Antara Waist To Height Ratio (WHtR) Dengan Heart Rate Recpvery (HRR) Pada Subyek Remaja Laki-laki Rizqi Husni Mudzakkir; Agus Prastowo; Khusnul Muflikhah
JURNAL NUTRISIA Vol 18 No 1 (2016): Maret 2016
Publisher : Poltekkes Kemenkes Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (82.977 KB) | DOI: 10.29238/jnutri.v18i1.85

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Background: The prevalence of obesity and cardiovascular disease remains a national problem. Banyumas, Central Java, is one of the districts where the prevalence of obesity and the risk of cardiovascular disease are high. WHtR is an anthropometric index that can be a parameter for early detection of cardiovascular disease risks. HRR is a physiological indicator of the heart’s function that can be associated with cardiovascular disease in adolescence. Objective: To determine the association between WHtR and HRR in adolescent boys. Methods: This is an analytic observational study with cross sectional approach. Total research subjects were 128 adolescent boys were divided into two groups: normal WHtR (n = 64) and abnormal WHtR (n = 64). WHtR data was obtained from ratio of waist circumference and height. HRR data was measured after the Kasch Step Test. Association between WHtR and HRR was analyzed using the Chi -square test (α = 0.05, 95% CI). Results: Value of WHtR in adolescent boys had a range of 0.34 - 0.70 with a mean of 0.49 ± 0.08. Value of HRR in adolescent boys had a range of 1-58 bpm with a mean of 20.63 ± 13.42 bpm. Chi-square test’s result was p=0.000, show there was a statistically significant association (p <0.05) between WHtR and HRR with the prevalence ratio (PR) = 3. Conclusion: There is an association between WHtR and HRR in adolescent boys. Adolescent boys with abnormal WHtR have 3 times higher risk obtaining a low HRR value than adolescent boys with normal WHtR. Keywords: waist to height ratio, heart rate recovery, adolescent boys
Co-Authors Gesa Gestana A Hernayanti Hernayanti Khusnul Muflikhah Pugud Samodro Rizqi Husni Mudzakkir