Hartono Kosim
Faculty of Medicine, Universitas Pelita Harapan, Tangerang, Indonesia

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Update on scrofuloderma Marianto Marianto; Hartono Kosim; Pande Agung Mahariski; Paulus Mario Christopher
Bali Dermatology and Venereology Journal Vol. 2 No. 2 (2019)
Publisher : DiscoverSys Inc

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15562/bdv.v2i2.20

Abstract

Tuberculosis is one of the most significant diseases which causes death worldwide. TB infection is assumed to infect the lungs only from a general perspective. In fact, TB infection also causes lesions on the skin. Scrofuloderma, as one of the most common types of cutaneous tuberculosis, often misdiagnosed and managed improperly due to its similarity with abscess. In addition, there were still no national and international guidelines for scrofuloderma. This review to give insights and review about an update in the basic principle of scrofuloderma and management.
Buschke-Lowenstein tumour (BLT)/giant condyloma acuminatum (GCA): an immunopathogenesis insight Paulus Mario Christopher; Hartono Kosim; Ratna Sari Wijaya; Silvi Suhardi; Linda Julianti Wijayadi
Bali Dermatology and Venereology Journal Vol. 3 No. 1 (2020)
Publisher : DiscoverSys Inc

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15562/bdv.v%vi%i.27

Abstract

Buschke Lowenstein tumor (BLT)/giant condyloma acuminatum is a rare variant of a sexually transmitted infection caused by human papillomavirus (HPV) type 6 and 11. HPV has its viral factors that exist to avoid immune surveillance and control through 1) infecting only the basal layer of the epithelium, 2) downregulation of host immunity, 3) suppression of proinflammatory proteins essential for viral clearance. The incidence of BLT/GCA is estimated to be 0.1% in the general population, with males having 2.7 times increased risk than females. A BLT/GCA is characterized by verrucous tumor or palpable cauliflower-likemass, exophytic growth, flesh-colored, and uneven surface. The definitive diagnosis of BLT/GCA is typical morphology along with histopathological examination, and/or viral serotyping. Treatment of BLT/GCA requires a multidisciplinary approach, determined based on age, the extent of the lesion, organ involvement, and organ location.
Update on scrofuloderma Marianto; Hartono Kosim; Pande Agung Mahariski; Paulus Mario Christopher
Bali Dermatology Venereology and Aesthetic Journal BDVJ - Vol. 2 No. 2 (December 2019)
Publisher : Explorer Front

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51559/vygwv246

Abstract

Tuberculosis is one of the most significant diseases which causes death worldwide. TB infection is assumed to infect the lungs only from a general perspective. In fact, TB infection also causes lesions on the skin. Scrofuloderma, as one of the most common types of cutaneous tuberculosis, often misdiagnosed and managed improperly due to its similarity with abscess. In addition, there were still no national and international guidelines for scrofuloderma. This review to give insights and review about an update in the basic principle of scrofuloderma and management.
Buschke Lowenstein tumor (BLT)/giant condyloma acuminatum (GCA): An immunopathogenesis insight Paulus Mario Christopher; Hartono Kosim; Ratna Sari Wijaya; Silvi Suhardi; Linda Julianti
Bali Dermatology Venereology and Aesthetic Journal BDVJ - Vol. 3 No. 1 (June 2020)
Publisher : Explorer Front

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51559/kajdxg43

Abstract

Buschke Lowenstein tumor (BLT)/giant condyloma acuminatum is a rare variant of sexually transmitted infection caused by human papillomavirus (HPV) type 6 and 11. HPV has its viral factors that exist to avoid immune surveillance and control through 1) infecting only the basal layer of the epithelium, 2) downregulation of host immunity, 3) suppression of proinflammatory proteins essential for viral clearance. The incidence of BLT/GCA is estimated to be 0.1% in the general population, with males having 2.7 times increased risk than females. The definitive diagnosis of BLT/GCA is typical morphology along with histopathological examination, and/or viral serotyping. Treatment of BLT/GCA requires a multidisciplinary approach, determined based on age, the extent of the lesion, organ involvement, and organ location.