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All Journal International Journal of Industrial Research and Applied Engineering The International Journal of Medical Science and Health Research
Billy Jonathan
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Computer Science & IT Control & Systems Engineering Dentistry Electrical & Electronics Engineering Health Professions Industrial & Manufacturing Engineering Mechanical Engineering Medicine & Pharmacology Nursing Public Health Veterinary

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Create Domain-Specific Language and Syntax Checker Using Xtext Billy Jonathan; Rafayel Avetyan; Stan Abeln
International Journal of Industrial Research and Applied Engineering Vol 4, No 1: APRIL 2019
Publisher : Institute of Research and Community Outreach - Petra Christian University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.9744/jirae.4.1.26-32

Abstract

ASML is a company that manufactures the TWINSCAN machine that can produce semiconductor chips. This machine has a TWINSCAN software installed inside it and that software needs mapping configuration files to keep it running properly. The configuration files are developed by developers from many departments within ASML. However, the development process of the configuration files is ineffective, as the developers will know if there is any defect in the source code only in the late part of the development after all files have been committed into the TWINSCAN software’s source code archive. It would be better if the developers know if there is any invalid syntax in the configuration files when they are still creating or editing the files, so they can fix the defects immediately before the files are uploaded into the source code archive. The main purpose of this research is to develop a Domain-Specific Language (DSL) based on the structure of the configuration files, and a syntax checker application that can check the mapping configuration files for the TWINSCAN machine during the creation or editing phase of those files by the developers. The development of the DSL and syntax checker would be done using Xtext framework installed in Eclipse Integrated Development Environment (IDE). The final results show that the DSL and the syntax checker developed using Xtext can detect any invalid syntax during the development phase of the configuration files, so the developers can fix the defects directly, thus solving the company’s problem.
What is The Progression of Joint Deformity and Disability in Rheumatoid Arthritis Patients with Different Treatment Approaches? : A Systematic Review Billy Jonathan; Veronica Winda Soesanto; Chaira Sultana Mazaya
The International Journal of Medical Science and Health Research Vol. 13 No. 1 (2025): The International Journal of Medical Science and Health Research
Publisher : International Medical Journal Corp. Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70070/vtj3wd73

Abstract

Introduction: Rheumatoid Arthritis (RA) is a chronic autoimmune disease leading to progressive joint destruction and disability. Modern management has shifted towards early, aggressive "treat-to-target" strategies to halt disease progression. This systematic review evaluates the progression of joint deformity and disability in RA patients under various treatment approaches. Methods: Following PRISMA guidelines, we systematically reviewed randomized controlled trials from PubMed, Springer, Semantic Scholar, and Google Scholar. We included studies on adult RA patients with at least a 12-month follow-up that assessed joint deformity or functional disability. Nine studies met the inclusion criteria for the final analysis. Results: Early, aggressive treat-to-target strategies resulted in minimal radiographic progression, with some studies showing a complete halt in joint damage over long-term follow-up of up to 10 years. Functional disability, measured by the Health Assessment Questionnaire (HAQ), improved across all pharmacological interventions. Non-pharmacological interventions, like complex rehabilitation, significantly improved functional status, reducing HAQ scores by up to 73.8%, but their effect on radiographic outcomes was not reported. Baseline anti-CCP positivity and high disease activity were predictors of poorer outcomes. Discussion: The evidence confirms that early and sustained pharmacological treatment is crucial for controlling structural damage and preserving function. Combining these treatments with non-pharmacological therapies like targeted exercise provides additional functional benefits. However, a gap remains in understanding the impact of non-pharmacological interventions on long-term joint structure. Conclusion: An integrated approach combining early, aggressive pharmacotherapy with adjunctive non-pharmacological interventions offers the most effective strategy for managing RA. This approach successfully limits joint deformity and improves patient disability and quality of life.
Co-Authors Chaira Sultana Mazaya Rafayel Avetyan Stan Abeln Veronica Winda Soesanto