Garuda - Garba Rujukan Digital

Leonov Rianto

Akademi Farmasi IKIFA

Author-ID : 4376072

Biochemistry, Genetics & Molecular Biology Chemistry Immunology & microbiology Medicine & Pharmacology Nursing Public Health

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UJI EFEKTIVITAS DAYA ANTHELMINTIK JUS BIJI MENTIMUN (CUCUMIS SATIVUM, L) TERHADAP CACING ASCARIDIA GALLI SECARA IN VITRO Leonov Rianto
INDONESIA NATURAL RESEARCH PHARMACEUTICAL JOURNAL Vol 1, No 1 (2016)
Publisher : Fakultas Farmasi Universitas 17 Agustus 1945 Jakarta

ABSTRACT Research has been conducted to review the efficacy of anthelmintic on seeing the juice of cucumber seeds ( Cucumis sativum , L ) Against Ascaridia galli by in vitro method . By experimental study was conducted , with samples of seeds of cucumber ( Cucumis sativum , L ) The smoothed and made with 3 concentrations That is 15 % , 30 % and 60 % . The experimental animals used is Ascaridia galli with negative control solution of NaCl 0.9 % and a positive control pyrantel pamoate suspension with concentrations of 0.2 % , 0.4 % and 0.6 % . The analysis of data is probit analysis be adopted . Results Of Research was claimed that the juice of cucumber seeds ( Cucumis sativum , L ) have anthelmintic efficacy against Ascaridia galli with 12.76 % LC50 and LT50 3 hours 4 minutes 39 seconds . Comparising withtables of LD50 value, the obtained dose is 472,59mg / kg and it is in no toxiccategory. Keywords : anthelmintic, Cucumis sativum, L, Ascaridia galli, pirantel pamoat. ABSTRAK Penelitian ini dilakukan untuk melihat khasiat anthelmintik pada jus biji mentimun (Cucumis sativum,L) terhadap cacing Ascaridia galli secara in vitro. Penelitian dilakukan secara eskperimental, dengan sampel biji mentimun (Cucumis sativum,L) yang dihaluskan dan dibuat dengan 3 konsentrasi yaitu 15%, 30% dan 60%. Hewan coba yang digunakan adalah cacing Ascaridia galli dengan kontrol negatif larutan NaCl 0,9% dan kontrol positif suspensi Pirantel pamoat dengan konsentrasi 0,2%, 0,4% dan 0,6%. Analisis data yang digunakakan adalah analisis probit. Hasil dari penelitian ini menyatakan bahwa jus biji mentimun (Cucumis sativum,L) mempunyai khasiat sebagai anthelmintik terhadap cacing Ascaridia galli dengan harga LC50 12,76% dan LT50 3 jam 4 menit 39 detik. Dosis perbandingan yang didapat 472,59mg/kgBB dan berada di kategori Praktis Tidak Toksis berdasarkan tabel nilai LD50. Kata Kunci: Anthelmintik, Mentimun (Cucumis sativum, L), cacing Ascaridia galli, pirantel pamoat.

UJI AKTIVITAS EKSTRAK ETANOL 96% BIJI SRIKAYA (Annona squamosa L.) SEBAGAI ANTIDIARE YANG DISEBABKAN OLEH BAKTERI Shigella dysenteriae DENGAN METODE DIFUSI CAKRAM Leonov Rianto; Indri Astuti Handayani; Annisa Septiyani
Jurnal Ilmiah Manuntung Vol 1 No 2 (2015): Jurnal Ilmiah Manuntung
Publisher : jurnal ilmiah manuntung sekolah tinggi ilmu kesehatan samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v1i2.33

This research aims to find out how to extract ethanol 96% seed custard apples as Antidiarrhoeal that is caused by bacteria Shigella dysenteriae with different concentrations and compare with chloramphenicol. In addition, also to find out whether their respective inhibitory power of concentration of ethanol 96% seed extract custard apples have a difference in meaning. Research done by experimental methods, was carried out in the laboratory of pharmaceutical Academy IKIFA. Testing was done using the diffusion disc method. The concentration of ethanol 96% seed extract custard apples are used i.e. 15%, 30%, 45%, 60%, and 75%. As positive controls used chloramphenicol 30 µg/ml and NaCl 0.9% as the negative control. Each test is carried out as many as eight repetitions. The results showed an average diameter drag power which formed on the test solution with a concentration of 15%, 30%, 45%, 60% and 75% respectively of 6,887 mm, 11,49 mm, 8,144 mm, 7,694 mm, 7,150 mm, whereas for chloramphenicol for 40,31 mm. Based on the results of the statistical tests there are meaningful differences between concentrations showed a meaningful difference between the concentration of 15% and 30%, 15% and 60% and 15% and 75%. Conclusion of this research is at a concentration of 15%, 96% ethanol extract of seeds of custard apples have been able to inhibit the growth of bacteria, Shigella dysenteriae

UJI EFEKTIVITAS DAYA ANTHELMINTIK JUS BIJI MENTIMUN (Cucumis Sativum, L) TERHADAP CACING ASCARIDIA GALLI SECARA IN VITRO Leonov Rianto; Indri Astuti; Ika Prihatiningrum
Jurnal Ilmiah Manuntung Vol 2 No 1 (2016): Jurnal Ilmiah Manuntung
Publisher : jurnal ilmiah manuntung sekolah tinggi ilmu kesehatan samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v2i1.38

Research has been conducted to review the efficacy of anthelmintic on seeing the juice of cucumber seeds ( Cucumis sativum , L ) Against Ascaridia galli by in vitro method . By experimental study was conducted , with samples of seeds of cucumber ( Cucumis sativum , L ) The smoothed and made with 3 concentrations That is 15 % , 30 % and 60 % . The experimental animals used is Ascaridia galli with negative control solution of NaCl 0.9 % and a positive control pyrantel pamoate suspension with concentrations of 0.2 % , 0.4 % and 0.6 % . The analysis of data is probit analysis be adopted . Results Of Research was claimed that the juice of cucumber seeds ( Cucumis sativum , L ) have anthelmintic efficacy against Ascaridia galli with 12.76 % LC50 and LT50 3 hours 4 minutes 39 seconds . Comparising with tables of LD50 value, the obtained dose is 472,59mg / kg and it is in no toxic category.

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