Nia Sahra Labetubun
Program Studi Pendidikan Dokter, Fakultas Kedokteran, Universitas Muhammadiyah Surakarta

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REFA (REHABILITASI FRIEDREICH’S ATAXIA) SEBAGAI UPAYA PENINGKATAN KUALITAS HIDUP PENDERITA DI KECAMATAN AMPEL BOYOLALI Zaenabu, Lina; Labetubun, Nia Sahra; Sitta, Alfi Nurmas; Dewanti, Ajeng Aprilia
Program Kreativitas Mahasiswa - Pengabdian Kepada Masyarakat PKM-M 2013
Publisher : Ditlitabmas, Ditjen DIKTI, Kemdikbud RI

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Abstract

Genetic disorders are the most common coordination in the world is Fridreich s ataxia (FA). In Indonesia FA obtained Boyolali Ampel area. FA is progressive and has not found specific drugs for FA. Symptoms and accompanying complications can be treated with physical exercise. Physical exercise can reduce the progression of symptoms and helps maintain body functions as long as possible. The level of knowledge of patient and public awareness about the FA in Boyolali Ampel sub-district is still lacking. Improving the quality of life and slow the worsening condition of the patient FA. Divided into three phases, namely the preparation, implementation, and follow-up. In the implementation phase given counseling or education, provide motivation and physical exercise through video playback, provide physical exercise posters, and pocket books to be handgrip patients, provision of aids to patients, perform a physical examination, and renovate one of the stalls where people work. In the follow-up stage of the final observation assessment to measure the success of this program and reinforce the benefits of patients. Improved quality of life is evident from the scores of healthy physical (exercise 58.33% to 93.33%, the cleanliness of 66.7% to 85%, and the nutritional 71.67% to 78.33%), healthy social (65% to 75%), a healthy spiritual (85% to 91, 67%), support family members as the cadre (71.67% to 93.33%), the increase in scores independence and decrease depression scores. Worsening condition of the patient can be slowed as evidenced by an increase in the percentage of physical exercise. Physical exercise and family support is very influential in improving the quality of life of patients.
The Impact of Air Pollution on Lung Development and Physical Growth in Early Childhood: A Systematic Review of Risk Factors and Long-Term Effects Ariani; Labetubun, Nia Sahra; Mafazi, Hashfi
Sriwijaya Journal of Medicine Vol. 8 No. 2 (2025): Vol 8, No 2, 2025
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/sjm.v8i2.317

Abstract

Children in developing countries are highly vulnerable to respiratory health problems caused by air pollution. Exposure during pregnancy and early life critically influences lung development and physical growth, with potential long-term consequences. This systematic review aimed to assess the effects of prenatal and early childhood exposure to air pollution on lung development and physical growth, and to identify risk factors that may influence these outcomes. A systematic search was conducted in February 2025 across Scopus, PubMed, and Web of Science databases. Studies published in English between 2015 and 2025 were screened using PRISMA guidelines and assessed for quality using the ROBINS-I tool. From 1,303 records, 28 studies met the inclusion criteria. Twenty-one studies (75%) reported reductions in lung function parameters such as FEV₁, FVC, and FEF25–75% in association with pollutants including PM2.5, NO₂, O₃, and PAHs. Three studies reported increased risk of stunting, primarily linked to indoor air pollution and biomass fuel exposure. These outcomes were associated with mechanisms such as oxidative stress, systemic inflammation, and epigenetic changes. The second trimester of pregnancy and the first two years of life were identified as critical exposure windows. Risk was modified by age, sex, socioeconomic status, breastfeeding duration, and home ventilation. Air pollution exposure during sensitive developmental periods impairs lung function and physical growth in children. Urgent public health measures—promoting clean energy, improving indoor air quality, and reducing exposure in vulnerable groups—are essential to support healthy childhood development.