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All Journal Jurnal Riset Kimia Maklumat: Journal of Da'wah and Islamic Studies
Khalid Hussain
Unknown Affiliation
Religion Humanities Chemistry Education Social Sciences

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IN VITRO ANTIANGIOGENESIS ACTIVITY OF STANDARDIZED EXTRACTS OF Piper sarmentosum Roxb Khalid Hussain; Zhari Ismail; Amirin Sadikun; Pazilah Ibrahim; Amin Malik
Jurnal Riset Kimia Vol. 1 No. 2 (2008): March
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jrk.v1i2.50

Abstract

 ABSTRACT This study was undertaken to investigate the antiangiogenesis activity of standardized extracts/fractions of the leaf of Piper sarmentosum, using rat aorta model. The pulverized leaf was extracted sequentially and methanol extract was further fractionated with hexane, chloroform and ethylacetate. Both extracts and fractions were standardized by reverse phase HPLC with UV detection at 260 nm, using two markers, sarmentine and sarmentosine. Chloroform and methanol extracts have exhibited antiangiogenesis activity of 100% and 20% respectively. Antiangiogenesis activity of hexane and chloroform fractions was found to be 10% and 90% respectively, while ethylacetate fraction was found to be inactive. The analysis of most active extract and fraction has exhibited different profile by HPLC on the basis of amides. This study indicates that chloroform extract and fraction have promising antiangiogenesis activity and have potential for diseases involving angiogenesis. Keywords : antiangiogenesis activity, Piper sarmentosum Roxb.
A Spiritual Prescription for the Sick Khalid Hussain; Hüseyin Çaksen
Maklumat: Journal of Da'wah and Islamic Studies Vol. 4 No. 1 (2026)
Publisher : Penerbit Hellow Pustaka

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61166/maklumat.v4i1.111

Abstract

This review examines Message for the Sick, drawn from the Twenty-Fifth Flash of Said Nursi’s Risale-i Nur, highlighting its theological depth and pastoral sensitivity. Nursi reframes illness as spiritually meaningful states rooted in divine wisdom, presenting suffering not as punishment but as a pathway to understanding God’s attributes. His remedies for the sick offer a Qur’an-centred lens through which vulnerability becomes a source of insight, patience, and inner transformation. Through close textual analysis, this review demonstrates how Nursi’s reflections integrate Islamic spirituality, ethical psychology, and metaphysical reasoning. The treatise ultimately provides a holistic and timeless model of spiritual care relevant for clinicians, caregivers, and readers seeking to understand hardship through faith.
Co-Authors Amin Malik Amirin Sadikun Hüseyin Çaksen Pazilah Ibrahim Zhari Ismail