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IN VITRO STUDIES ON CALCIUM OXALATE CRYSTAL GROWTH INHIBITION OF STROBILANTHES CRISPUS EXTRACTS Afrizal Itam; Zhari Ismail; Amin Malik Shah Abdul Majid
Jurnal Riset Kimia Vol. 3 No. 1 (2009): September
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jrk.v3i1.30

Abstract

 ABSTRACT Strobilanthes crispus L. (Acanthaceae) has been used locally in traditional medicine for kidney stone and related diseases. These plant extracts have the ability to inhibit the calcium oxalate crystal growth, where the ability of water extract is higher than those of the 70% acetone, methanol and acetone extracts. The ability to inhibit the calcium oxalate crystal growth of these extracts is lower than that of sodium citrate as positive control. Keywords: Strobilanthes crispus, Acanthaceae, crystal inhibition, calcium oxalate
Kajian Fitokimia, Kandungan Fenolik dan Flavonoid Total, serta Aktivitas Antioksidan Ekstrak Buah Rimbang (Solanum torvum Sw.) Afrizal Itam; Natasya Dwi Putri; Winda Hardani; Suryati
Jurnal Kimia Unand Vol. 14 No. 1 (2025): May 2025
Publisher : Departemen Kimia Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jku.14.1.11-16.2025

Abstract

Solanum torvum Sw is one of the medicinal plants which is utilized by the community as a food ingredient and herbal medicine. The aims this study is to determine of secondary metabolite compounds, total phenolics and flavonoids content, and antioxidant activity using DPPH method from S. torvum fruit extracts. The results show that S. torvum contains secondary metabolite compounds involves flavonoids, phenolics, steroids, saponins, alkaloids and coumarins. Total phenolic content of hexane, ethyl acetate and aqueous fractions were 49.0, 72.7 and 45.0 mg GAE/g sample, respectively. Meanwhile, total flavonoid content of hexane, ethyl acetate and aqueous fractions were 53.8, 199.2 and 57,7 mg QE/g sample, respectively. Antioxidant activity that expressed with IC50 value were categorized as very powerfull antioxidant to DPPH for hexane and ethyl acetate fractions IC50 37.12 and 2.36 mg/L), while aqueous fraction was categorized strong activity (IC50 84.9 mg/L)