Anjani Putri Retnaninggalih, Anjani Putri
Mahasiswa Fakultas Kedokteran, Unversitas Jember

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The Comparison of Bay Leaf and Celery Leaf Infusion Effect on Decreasing LDL Level in Dyslipidemic Wistar Rats Model Retnaninggalih, Anjani Putri; Efendi, Erfan; Hairrudin, Hairrudin
Journal of Agromedicine and Medical Sciences Vol 1, No 1 (2015)
Publisher : Medical Faculty of Jember University (Fakultas Kedokteran Universitas Jember)

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Abstract

Coronary heart disease (CHD) is the cause of 7,3 million death globally in 2008. The main pathophysiology process that leads to CHD is atherosclerosis which is caused by high LDL cholesterol level. The aim of this study was to explore bay leaf and celery leaf infusion effect on reducing LDL cholesterol level in dyslipidemic rat model. The type of this study was true experimental research using wistar rat (Rattus novergicus) as the sample. The rats were induced by high fat diet and PTU for two weeks then each of the group were given either bay leaf infusion, celery leaf infusion, simvastatin (positive control), or aquadest (negative control) for a week. The measurement of LDL level used Friedewald formulation. Data was analyzed using paired sample t test and one way ANOVA. As the result there was a significance reduction on LDL level after treatment with bay leaf (p=0,013) and celery leaf infusion (p=0,035) but there was no significance difference between groups (p=0,293). It was concluded that bay leaf and celery leaf infusion could reduce the LDL level in dyslipidemic wistar rat but there was no difference on the capability of the two different leafs on reducing LDL level. Keywords: dyslipidemia, LDL, bay leaf, celery leaf, wistar rats  
THE EFFECTIVENESS OF EDUCATION IN INCREASING HYPERTENSION KNOWLEDGE IN HYPERTENSION PATIENTS AT THE PRATAMA CLINIC UIN SUNAN AMPEL SURABAYA Asiyah, Siti Nur; Rizqiah, Dhuhrotul; Retnaninggalih, Anjani Putri; Suyatno, Restiani L.; Winarto, Agnestria; Zahroh, Aini Nurul Fatimatuz; Najjah, Alisa Hidayatun; Syaroh, Roza Maulida Muhanna; Purwati, Nur Fatihah
HEARTY Vol 12 No 1 (2024): FEBRUARI
Publisher : Fakultas Ilmu Kesehatan, Universitas Ibn Khaldun, Bogor

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32832/hearty.v12i1.8417

Abstract

Hypertension is a condition where the systolic blood pressure is 130 mmHg or diastolic is 80 mmHg; 80 – 95% in cases of essential hypertension. Hypertension can also be called the "silent killer" because hypertension does not show real symptoms, but can lead to life-threatening complications such as coronary heart disease, stroke, kidney failure and heart failure. Hypertension is also the biggest cause of the percentage of the population who have health complaints or disease morbidity in the world. Hypertension sufferers are estimated to reach 1.5 billion in 2025 and deaths can reach 9.4 million individuals. The purpose of this study was to determine the effectiveness of education in increasing knowledge of hypertension in patients with hypertension at the Pratama Clinic of Sunan Ampel State Islamic University (UINSA) Surabaya. The population in this study were patients with hypertension at the Primary Clinic UINSA Surabaya as many as 14 people. This study uses a quantitative method with One-Group Pretest-Posttest Design. The results of the study using the Mc Nemar statistical test obtained a value of = 0.031 <0.05. That is, providing education is effective in increasing knowledge of hypertension in hypertension patients at the UINSA Primary Clinic Surabaya.