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PERBANDINGAN FUNGSI KOGNITIF PADA AKSEPTOR PIL KB KOMBINASI DENGAN AKSEPTOR SUNTIK KB 1 BULAN DI WILAYAH KERJA PUSKESMAS PASAYANGAN Yasmin, Alfi; Noor, Meitria Syahadatina; Mahmudah, Riva’atul
IKESMA Vol 6, No 1 (2010)
Publisher : FKM - UNEJ

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (506.5 KB)

Abstract

Family Planning National Program is a program designed by government with the aim to control birthrate, one of which is the hormonal method, that contained estrogen and progesterone hormones. Aside from its sexual  and reproductive functions, estrogen can be used to prevent the degradation of cognitive function. The purpose of this research was to find out the comparison of cognitive function of oral contraceptive users  and the monthly injected contraceptive users by using Mini Mental State Examination (MMSE) test in the area Pasayangan Public Health Center Kabupaten Banjar. It was an analytic observational study, with cross sectional design, and the subjects were 30 oral users and 30 monthly injected contraceptive users in the area Pasayangan Public Health Center Kabupaten Banjar. The result of this study indicated that there were 18 monthly injected contraceptive users who had good cognitive function, bigger in number than the oral contraceptive users (13 subjects). Analysis with Mann-Whitney test gave p value of  0.026 (p < 0.05), which showed that there was a significant difference between oral contraceptive users and monthly injected contraceptive users. It could be concluded that the cognitive function of monthly injected contraceptive users were significantly higher than oral contraceptive users. Keywords: oral contraceptives, injected contraceptives, estrogen, cognitive function
Efek Jus Buah Karamunting (Melastoma malabathricum L.) Terhadap Kadar Trigliserida Serum Darah Tikus Putih Yang Diinduksi Propiltiourasil Noorrafiqi, Muhammad Ichwan; Yasmin, Alfi; Hendriyono, FX
Jurnal Berkala Kedokteran Vol 9, No 2 (2013): September 2013
Publisher : Pendidikan Dokter Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jbk.v9i2.952

Abstract

ABSTRACT: This study was aimed to understand the effect of karamunting fruit juice on triglyceride serum level in white rats induced with propylthiouracil (PTU). This study design was experimental, conducted on 7 groups, that is, group I who was not given any treatments (normal group), group II who was given PTU and labelled as negative control, group III who was given PTU and fenofibrate and labelled as positive control, group IV-VII who were given PTU and karamunting fruit juice. Result showed that the average values of triglyceride level in  group VI-VII were 105 mg/dL, 222.75 mg/dL, 85.25 mg/dL, 123 mg/dL, 135.25 mg/dL, 132 mg/dL, and 122.5 mg/dL, respectively. There were significant differences between group II and groups VI-VII who were given karamunting fruit juice. It was concluded that karamunting fruit juice from the dose of 1 mg/gBW could inhibit the increase in triglyceride serum level in white rats induced with PTU and given cholesterol diet. Keywords: karamunting juice, triglyceride, propylthiouracil ABSTRAK: Penelitian ini bertujuan mengetahui efek jus buah karamunting terhadap kadar trigliserida pada tikus putih yang diinduksi propiltiourasil (PTU). Penelitian ini bersifat eksperimental yang dilakukan pada 7 kelompok, yaitu kelompok I yang tidak diberikan perlakuan (kelompok normal), kelompok II yang diberi PTU sebagai kontrol negatif, kelompok III yang diberi PTU dan fenofibrat sebagai kontrol positif, dan kelompok IV-VII yang diberi PTU dan jus buah karamunting. Hasil penelitian menunjukkan rerata kadar trigliserida pada kelompok I-VII berturut-turut adalah sebesar 105 mg/dL, 222,75 mg/dL, 85,25 mg/dL, 123 mg/dL, 135,25 mg/dL, 132 mg/dL, dan 122,5 mg/dL. Terdapat perbedaan bermakna antara kelompok II dan kelompok VI-VII yang diberikan jus buah karamunting. Dapat disimpulkan bahwa jus buah karamunting mulai dosis 1 mg/gBB dapat menghambat peningkatan kadar trigliserida dalam serum darah tikus putih yang diberi pakan kolesterol dan diinduksi PTU. Kata-kata kunci: jus buah karamunting, trigliserida, propiltiourasil