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All Journal Jambi Medical Journal : Jurnal Kedokteran dan Kesehatan Majalah Kedokteran Bandung Althea Medical Journal Journal of Medicine and Health
Abdul Hadi Hassan, Abdul Hadi
Department of Pathology Anatomy Faculty of Medicine Universitas Padjadjaran/Dr. Hasan Sadikin General Hospital Bandung
Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Public Health

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Journal : Althea Medical Journal

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The Protective Effect of Field Mint Leaves in Reducing Stomach Ulcer in Rats Induced by Aspirin Krisnan, Vanitha Ratha; Rachman, Januarsih A.; Hassan, Abdul Hadi
Althea Medical Journal Vol 2, No 3 (2015)
Publisher : Althea Medical Journal

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (529.025 KB)

Abstract

Background: Stomach mucosal wall erosion is caused by the imbalance of the aggressive factors and mucosal defensive factors due to the common causes such as the side effect of consuming non-steroidal anti-inflammatory drugs. Field mint (Menthaarvensis) leaves have been used as an alternative option to cure and prevent the gastric problems. The aim of this study was to analyze the protective effect of Field mint leaves infusion in reducing stomach ulcer in rats induced by Aspirin.Methods: The experimental study was conducted at Histology Laboratory of Faculty of Medicine, Universitas Padjadjaran, Bandung. Sixteen rats were divided into 4 groups randomly: group I (control negative group), group II (control positive group, given 90mg/day Aspirin, group III (the treatment group, given 5cc of Field mint leaves infusion and 90 mg Aspirin) and group IV (the treatment group, given 5.6µg of Misoprostol and 90 mg Aspirin). Mucosal wall erosions were determined by using microscope. Data were analyzed using non-parametric Kruskal-Wallis test and Mann-Whitney U-test (CI 95% and p-value<0.05)Results: Group II had high score of mucosal wall erosions after given only aspirin. In group III and IV, the score of mucosal wall erosions were low. However there was no difference in score of mucosal wall erosions between group III-IV (p<0.05)Conclusions: Field mint (Menthaarvensis) leaves infusion is able to prevent stomach mucosal wall erosions induced by Aspirin as misoprostol does. DOI: 10.15850/amj.v2n3.496
Association between Age and Histopathological Grade of Bladder Urothelial Carcinoma Alby, Dionisius; Hassan, Abdul Hadi; Sibarani, Jupiter
Althea Medical Journal Vol 4, No 4 (2017)
Publisher : Althea Medical Journal

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (573.006 KB) | DOI: 10.15850/amj.v49n4.1263

Abstract

Background: Bladder cancer, particularly urothelial carcinoma, is prevalent in male and ≥55 years old population. Grade of the bladder tumor affects clinical characteristics, management, and prognosis of the patient. This study aimed to analyze the association between age and histopathological grade of bladder urothelial carcinoma. Methods: This cross-sectional analytical study was approved by the Ethical Clearance Committee of Dr. Hasan Sadikin General Hospital, involving 241 medical records of bladder urothelial carcinoma patients in the Department of Anatomical Pathology at Dr. Hasan Sadikin General Hospital during 2009–2013. Chi-square test was applied to 45 patients with complete record of histopathological grade.Results: Most of the subjects were 65 years old. Male patients were the most frequent. The proportion of low-grade carcinoma in <65 years old age group was only 39.1%, while in ≥65 years old age group was 72.7%. The proportion of high-grade carcinoma in <65 years old age group reached 60.9%, which was 27.3% higher than in ≥65 years old age group. Chi-square test result showed a statistically significant difference between histopathological grade of urothelial carcinoma in <65 years and ≥65 years age groups (p=0.023).Conclusions: Proportion of high-grade and low-grade urothelial carcinoma between <65 years and ≥65 years age groups are statistically different; therefore, an association between age and histopathological grade of bladder urothelial carcinoma is shown. 
Co-Authors Alby, Dionisius Antonius Janes Ridwan, Antonius Janes Bethy S Hernowo, Bethy S Bethy S. Hernowo Erida, Yulie Fenny Ariyanni, Fenny Hasrayati Agustina Hermin Aminah Usman Herry Yulianti Januarsih A. Rachman, Januarsih A. Jupiter Sibarani Odilia Dos Reis, Odilia Dos Sri Suryanti Vanitha Ratha Krisnan, Vanitha Ratha