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Dona Dewi Nirlawati
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Biochemistry, Genetics & Molecular Biology Medicine & Pharmacology

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HUBUNGAN TINGKAT PENDAPATAN KELUARGA DENGAN STATUS GIZI BALITA DI WILAYAH KERJA PUSKESMAS KALIJAMBE Handini, Dian; Ichsan, Burhannudin; Nirlawati, Dona Dewi
Biomedika Vol 5, No 2 (2013): Biomedika Agustus 2013
Publisher : Universitas Muhamadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

The state of nutritional status of children in Central Java based on index of height for age data obtained 16.9% of children who have growth in a very short, short 17.0% of infants and 66.1% of normal infants. Economic growth in Sragen in 2000 was 2.85%, decreased in 2001 to 2.26%, and increased in 2002-2003, respectively 2.93% and 3.26%. Research methode was observational cross sectional analytic approach. The number of samples was 65 toddlers. Data analysis using Chi Square. The nutritional status of children by index weight for age (W/A) were experiencing malnutrition while the remaining 13.8% as having good nutrition as much as 86.2%, and the index based on height for age (H/A) which had malnutrition as much as 46.2% while the rest had good nutrition as much as 53.8%, while the index by weight according to height (W/H) were experiencing malnutrition while the remaining 13.8% as having good nutrition as much as 86.2% . The results of the analysis obtained p count is 0.009 to the sample distribution based on W/A, and 0.010 for sample distribution based H/A, and 0.009 for the distribution of the sample by W/H. There is a relationship between the level of family income to the nutritional status of children in the working area Public Health Center Kalijambe.Keywords: Family Income, Nutritional Status of Children
UJI EFEK PEMBERIAN EKSTRAK ETANOL 70% BIJI BUAH TERUNG UNGU (SOLANUM MELONGENA L.) TERHADAP KADAR KOLESTEROL HDL SERUM DARAH TIKUS PUTIH JANTAN (RATTUS NORVEGICUS) GALUR WISTAR Fajriyatun, Baiq Nova; Sutrisna, EM; Nirlawati, Dona Dewi
Biomedika Vol 6, No 1 (2014): Biomedika Februari 2014
Publisher : Universitas Muhamadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Extract of eggplant fruit (Solanum melongena L.) seed is a plant that has anti-hypercholesterolemia effect on the state of dyslipidemia. One of the compounds contained in them are fl avonoids nasunin which can increase levels of HDL cholesterol (high density lipoprotein). HDL cholesterol is considered as a compound have the ability to remove excess cholesterol from the arteries, and therefore called good cholesterol. This study is a laboratory experimental research using pretest and posttest control group. The sample consisted of 25 rats were divided into 5 groups. Group I is a negative control (-), Group II is a positive control (+), group III was treated 1 (dose 1), group IV was treated 2 (dose 2), and V is the treatment group 3 (dose 3). Each group was given a high-cholesterol diet. Negative and positive control group were not given the extract of fruit seed of eggplant, the treatment groups III, IV, and V were given the extract of fruit seed of eggplant with each dose of 20 mg/kg, 40 mg/kg, 80 mg/kg were given for 4 weeks. HDL cholesterol levels will be measured before and after cholesterol diet and calculated each week after giving of the extract. The data obtained tested with statistical tests One-Way Anova. HDL cholesterol positive control group and the treatment group showed signifi cant differences between groups. Treatment groups 1 and 2 levels of HDL cholesterol lower than the positive control group and the treatment group 3. Extract of eggplant fruit seed dose of 80 mg/kg show an increase in HDL cholesterol levels were signifi cantly (p <0.05). The 70% ethanol extract of eggplant fruit seed at a dose of 80 mg/kg can increase HDL cholesterol levels signifi cantly.Keywords : extract of eggplant fruit seed, hypercholesterol, HDL cholesterol
PERBEDAAN KADAR KOLESTEROL TOTAL ANTARA PENDERITA STROKE ISKEMIK DAN STROKE HEMORAGIK Aini, Athiefah Qurrotul; Pujarini, Listyo Asist; Nirlawati, Dona Dewi
Biomedika Vol 8, No 2 (2016): Biomedika Agustus 2016
Publisher : Universitas Muhamadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/biomedika.v8i2.2909

Abstract

Stroke merupakan penyebab kematian ketiga di dunia, setelah penyakit jantung dan kanker. Kadar lipid merupakan salah satu faktor yang berpengaruh pada morbiditas jangka pendek akibat stroke, sehingga evaluasi perbedaan kadar lipid pada subtipe stroke sangat penting dilakukan. Tujuan penelitian adalah untuk mengetahui apakah terdapat perbedaan kadar kolesterol total antara penderita stroke iskemik dan stroke hemoragik.Penelitian ini menggunakan desain penelitian observasional analitik dengan pendekatan cross sectional. Data diambil dari rekam medik pasien rawat inap di RS X Surakarta tahun 2014-2015. Sampel terdiri atas 30 penderita stroke iskemik dan 30 penderita stroke hemoragik. Analisa data dengan Uji T Tidak Berpasangan menunjukkan hasil p=0,005. Kadar kolesterol total pada penderita stroke iskemik memiliki rerata 202±33,9 mg/dL, lebih tinggi daripada penderita stroke hemoragik yang memiliki rerata 167,87±53,6 mg/dL. Kesimpulan dari penelitian adalah kadar kolesterol total pada penderita stroke iskemik lebih tinggi daripada penderita stroke hemoragik. Kata Kunci: Kadar Kolesterol Total, Kolesterol, Stroke Iskemik, Stroke Hemoragik
UJI EFEK PEMBERIAN EKSTRAK ETANOL 70% BIJI BUAH TERUNG UNGU (SOLANUM MELONGENA L.) TERHADAP KADAR KOLESTEROL HDL SERUM DARAH TIKUS PUTIH JANTAN (RATTUS NORVEGICUS) GALUR WISTAR Fajriyatun, Baiq Nova; Sutrisna, EM; Nirlawati, Dona Dewi
Biomedika Vol 6, No 1 (2014): Biomedika Februari 2014
Publisher : Universitas Muhamadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/biomedika.v6i1.282

Abstract

Extract of eggplant fruit (Solanum melongena L.) seed is a plant that has anti-hypercholesterolemia effect on the state of dyslipidemia. One of the compounds contained in them are fl avonoids nasunin which can increase levels of HDL cholesterol (high density lipoprotein). HDL cholesterol is considered as a compound have the ability to remove excess cholesterol from the arteries, and therefore called good cholesterol. This study is a laboratory experimental research using pretest and posttest control group. The sample consisted of 25 rats were divided into 5 groups. Group I is a negative control (-), Group II is a positive control (+), group III was treated 1 (dose 1), group IV was treated 2 (dose 2), and V is the treatment group 3 (dose 3). Each group was given a high-cholesterol diet. Negative and positive control group were not given the extract of fruit seed of eggplant, the treatment groups III, IV, and V were given the extract of fruit seed of eggplant with each dose of 20 mg/kg, 40 mg/kg, 80 mg/kg were given for 4 weeks. HDL cholesterol levels will be measured before and after cholesterol diet and calculated each week after giving of the extract. The data obtained tested with statistical tests One-Way Anova. HDL cholesterol positive control group and the treatment group showed signifi cant differences between groups. Treatment groups 1 and 2 levels of HDL cholesterol lower than the positive control group and the treatment group 3. Extract of eggplant fruit seed dose of 80 mg/kg show an increase in HDL cholesterol levels were signifi cantly (p <0.05). The 70% ethanol extract of eggplant fruit seed at a dose of 80 mg/kg can increase HDL cholesterol levels signifi cantly.Keywords : extract of eggplant fruit seed, hypercholesterol, HDL cholesterol
HUBUNGAN TINGKAT PENDAPATAN KELUARGA DENGAN STATUS GIZI BALITA DI WILAYAH KERJA PUSKESMAS KALIJAMBE Handini, Dian; Ichsan, Burhannudin; Nirlawati, Dona Dewi
Biomedika Vol 5, No 2 (2013): Biomedika Agustus 2013
Publisher : Universitas Muhamadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/biomedika.v5i2.263

Abstract

The state of nutritional status of children in Central Java based on index of height for age data obtained 16.9% of children who have growth in a very short, short 17.0% of infants and 66.1% of normal infants. Economic growth in Sragen in 2000 was 2.85%, decreased in 2001 to 2.26%, and increased in 2002-2003, respectively 2.93% and 3.26%. Research methode was observational cross sectional analytic approach. The number of samples was 65 toddlers. Data analysis using Chi Square. The nutritional status of children by index weight for age (W/A) were experiencing malnutrition while the remaining 13.8% as having good nutrition as much as 86.2%, and the index based on height for age (H/A) which had malnutrition as much as 46.2% while the rest had good nutrition as much as 53.8%, while the index by weight according to height (W/H) were experiencing malnutrition while the remaining 13.8% as having good nutrition as much as 86.2% . The results of the analysis obtained p count is 0.009 to the sample distribution based on W/A, and 0.010 for sample distribution based H/A, and 0.009 for the distribution of the sample by W/H. There is a relationship between the level of family income to the nutritional status of children in the working area Public Health Center Kalijambe.Keywords: Family Income, Nutritional Status of Children
UJI EFEK PEMBERIAN EKSTRAK ETANOL 70% BIJI BUAH TERUNG UNGU (SOLANUM MELONGENA L.) TERHADAP KADAR KOLESTEROL HDL SERUM DARAH TIKUS PUTIH JANTAN (RATTUS NORVEGICUS) GALUR WISTAR Baiq Nova Fajriyatun; EM Sutrisna; Dona Dewi Nirlawati
Biomedika Vol 6, No 1 (2014): Biomedika Februari 2014
Publisher : Universitas Muhamadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/biomedika.v6i1.282

Abstract

Extract of eggplant fruit (Solanum melongena L.) seed is a plant that has anti-hypercholesterolemia effect on the state of dyslipidemia. One of the compounds contained in them are fl avonoids nasunin which can increase levels of HDL cholesterol (high density lipoprotein). HDL cholesterol is considered as a compound have the ability to remove excess cholesterol from the arteries, and therefore called good cholesterol. This study is a laboratory experimental research using pretest and posttest control group. The sample consisted of 25 rats were divided into 5 groups. Group I is a negative control (-), Group II is a positive control (+), group III was treated 1 (dose 1), group IV was treated 2 (dose 2), and V is the treatment group 3 (dose 3). Each group was given a high-cholesterol diet. Negative and positive control group were not given the extract of fruit seed of eggplant, the treatment groups III, IV, and V were given the extract of fruit seed of eggplant with each dose of 20 mg/kg, 40 mg/kg, 80 mg/kg were given for 4 weeks. HDL cholesterol levels will be measured before and after cholesterol diet and calculated each week after giving of the extract. The data obtained tested with statistical tests One-Way Anova. HDL cholesterol positive control group and the treatment group showed signifi cant differences between groups. Treatment groups 1 and 2 levels of HDL cholesterol lower than the positive control group and the treatment group 3. Extract of eggplant fruit seed dose of 80 mg/kg show an increase in HDL cholesterol levels were signifi cantly (p 0.05). The 70% ethanol extract of eggplant fruit seed at a dose of 80 mg/kg can increase HDL cholesterol levels signifi cantly.Keywords : extract of eggplant fruit seed, hypercholesterol, HDL cholesterol
PERBEDAAN KADAR KOLESTEROL TOTAL ANTARA PENDERITA STROKE ISKEMIK DAN STROKE HEMORAGIK Athiefah Qurrotul Aini; Listyo Asist Pujarini; Dona Dewi Nirlawati
Biomedika Vol 8, No 2 (2016): Biomedika Agustus 2016
Publisher : Universitas Muhamadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/biomedika.v8i2.2909

Abstract

Stroke merupakan penyebab kematian ketiga di dunia, setelah penyakit jantung dan kanker. Kadar lipid merupakan salah satu faktor yang berpengaruh pada morbiditas jangka pendek akibat stroke, sehingga evaluasi perbedaan kadar lipid pada subtipe stroke sangat penting dilakukan. Tujuan penelitian adalah untuk mengetahui apakah terdapat perbedaan kadar kolesterol total antara penderita stroke iskemik dan stroke hemoragik.Penelitian ini menggunakan desain penelitian observasional analitik dengan pendekatan cross sectional. Data diambil dari rekam medik pasien rawat inap di RS X Surakarta tahun 2014-2015. Sampel terdiri atas 30 penderita stroke iskemik dan 30 penderita stroke hemoragik. Analisa data dengan Uji T Tidak Berpasangan menunjukkan hasil p=0,005. Kadar kolesterol total pada penderita stroke iskemik memiliki rerata 202±33,9 mg/dL, lebih tinggi daripada penderita stroke hemoragik yang memiliki rerata 167,87±53,6 mg/dL. Kesimpulan dari penelitian adalah kadar kolesterol total pada penderita stroke iskemik lebih tinggi daripada penderita stroke hemoragik. Kata Kunci: Kadar Kolesterol Total, Kolesterol, Stroke Iskemik, Stroke Hemoragik
HUBUNGAN TINGKAT PENDAPATAN KELUARGA DENGAN STATUS GIZI BALITA DI WILAYAH KERJA PUSKESMAS KALIJAMBE Dian Handini; Burhannudin Ichsan; Dona Dewi Nirlawati
Biomedika Vol 5, No 2 (2013): Biomedika Agustus 2013
Publisher : Universitas Muhamadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/biomedika.v5i2.263

Abstract

The state of nutritional status of children in Central Java based on index of height for age data obtained 16.9% of children who have growth in a very short, short 17.0% of infants and 66.1% of normal infants. Economic growth in Sragen in 2000 was 2.85%, decreased in 2001 to 2.26%, and increased in 2002-2003, respectively 2.93% and 3.26%. Research methode was observational cross sectional analytic approach. The number of samples was 65 toddlers. Data analysis using Chi Square. The nutritional status of children by index weight for age (W/A) were experiencing malnutrition while the remaining 13.8% as having good nutrition as much as 86.2%, and the index based on height for age (H/A) which had malnutrition as much as 46.2% while the rest had good nutrition as much as 53.8%, while the index by weight according to height (W/H) were experiencing malnutrition while the remaining 13.8% as having good nutrition as much as 86.2% . The results of the analysis obtained p count is 0.009 to the sample distribution based on W/A, and 0.010 for sample distribution based H/A, and 0.009 for the distribution of the sample by W/H. There is a relationship between the level of family income to the nutritional status of children in the working area Public Health Center Kalijambe.Keywords: Family Income, Nutritional Status of Children
Co-Authors Aini, Athiefah Qurrotul Athiefah Qurrotul Aini Baiq Nova Fajriyatun Baiq Nova Fajriyatun, Baiq Nova Burhannudin Ichsan Dian Handini Dian Handini, Dian Em Sutrisna Listyo Asist Pujarini Listyo Asist Pujarini, Listyo Asist