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All Journal Indonesian Journal of Cancer
Hartono Tjahjadi
Department of Pathological Anatomy, Doctor Cipto Mangunkusumo National General Hospital, Faculty of Medicine, Universitas Indonesia, Jakarta
Biochemistry, Genetics & Molecular Biology Immunology & microbiology Medicine & Pharmacology Public Health

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Magnetic Resonance Findings in Adolescent Vaginal Rhabdomyosarcoma: A Rare Case Report Trifonia Pingkan; Fitri Juniarta; Hartono Tjahjadi; Meliyana Lai
Indonesian Journal of Cancer Vol 16, No 1 (2022): March
Publisher : National Cancer Center - Dharmais Cancer Hospital

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1460.504 KB) | DOI: 10.33371/ijoc.v16i1.842

Abstract

Introduction: Rhabdomyosarcoma (RMS) is a rare soft tissue tumor, mainly affecting children, adolescents, and adults younger than 15 years, representing 3% to 4% of all childhood malignancies. Genitourinary is the second-most-common location of RMS with around 25% of cases. We describe a rare case of vaginal rhabdomyosarcoma in adolescents with huge polypoid tumors. Case Presentation: A 15-year-old female presented with vaginal bleeding for seven months. Her medical story was unremarkable. The clinical examination showed a polypoid mass prolapsed from the vagina, and the laboratory result was anemia. The pelvic magnetic resonance imaging (MRI) showed a heterogenous bulky solid tumor in the vagina. The histopathological finding revealed a sarcoma, and the immunohistochemical staining result was rhabdomyosarcoma not otherwise specified (NOS). Conclusions: Vaginal RMS is a rare malignant tumor of mesenchymal origin with skeletal muscle differentiation. Vaginal RMS is the most common site of genitourinary RMS and presents as a rapidly growing and aggressive local mass. Imaging plays an important role in the initial diagnosis of vaginal RMS, regarding the presentation of the bulky protruding tumor on the vaginal region
Co-Authors Fitri Juniarta Meliyana Lai Trifonia Pingkan