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All Journal Saintika Medika: Jurnal Ilmu Kesehatan dan Kedokteran Keluarga. CoMPHI Journal : Community Medicine and Public Health of Indonesia Journal
Isbandiyah
Universitas Muhammadiyah Malang
Health Professions Medicine & Pharmacology Nursing Public Health

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Pengaruh APGAR Family Terhadap Quality of Life Pasien Diabetes Mellitus Tipe 2 Feny Tunjungsari; Isbandiyah; Farajihan
CoMPHI Journal: Community Medicine and Public Health of Indonesia Journal Vol. 1 No. 1 (2020): Juni
Publisher : Perhimpunan Dokter Kedokteran Komunitas dan Kesehatan Masyarakat Indonesia (PDK3MI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (495.511 KB) | DOI: 10.37148/comphijournal.v1i1.5

Abstract

Introduction: Indonesia was a country from 10 countries that possesses the most dm prevalence of diabetes mellitus(DM) in urban areas amounting to 5.7 %. According to data center and health of the republic of indonesia, that theproportion of diabetes mellitus in the city of malang 2,3 %. The high number of diabetes mellitus in the city ofmalang is because the lack of the application of the family function well in people with DM type 2. Obstacles arisingthat is the majority of the community ignore this metabolic types of disease so that it cannot be detected earlier .Therole of family in aim diabetics mellitus type 2 believed to have the effect on the quality of life of sufferers DM. Aim ofstudy: This study aimed toanalyze function offamilies according to familyAPGAR to quality of life dm patients type2. Method: this study used an observational analytic with cross the sectional approach, 95 subjects were werechosen by simple random sampling. Data was analyzed using Spearman test. Results and Discussions: the resultsshowed a value of significance APGAR against quality of life as much as 0.000, which means there were asignificant relation exists (p < 0.05). A correlation coefficient APGAR against quality of life as much as 0.93, whichmeans of the nature of the strength of the relations is very strong. Conclusions: It can be concluded that there is avery strong influence (0.000) between APGAR family against quality of life the patient DMtype 2.
Ethanol Extract of Tamarind Fruit Increased Glomerular Area in Lead-Induced Wistar Rats Desy Andari; Muhammad Naufal Alzaky; Isbandiyah
Saintika Medika : Jurnal Ilmu Kesehatan dan Kedokteran Keluarga Vol. 22 No. 1 (2026): June 2026
Publisher : Universitas Muhammadiyah Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22219/sm.Vol22.SMUMM1.43903

Abstract

Lead (Pb) exposure is associated with nephrotoxicity, particularly structural alterations of the glomerulus mediated by oxidative stress. Tamarind fruit (Tamarindus indica L.) contains antioxidant compounds and vitamin C that may help attenuate lead-induced renal alterations. This study aimed to investigate the effect of ethanol extract of tamarind fruit on the glomerular area of Wistar rat kidneys exposed to lead. This experimental study conducted a post-test only control group design using 20 male Wistar rats. All groups were induced with lead acetate at a dose of 10 mg/kg body weight/day for 14 days. Treatment groups received ethanol extract of tamarind fruit (TFE) at doses of 12.5, 25, and 50 mg/kg body weight/day. Glomerular area was assessed histologically, and data were analyzed using one-way ANOVA and PostHoc. The results showed a significant difference in glomerular area among groups (p < 0.05). Administration of TFE at a dose of 12.5 mg/kg body weight/day demonstrated a more favorable glomerular area compared to the lead-only group, whereas higher doses did not show additional improvement. These findings suggest that low-dose TFE may influence glomerular structural changes induced by lead exposure.
Co-Authors Desy Andari Farajihan Feny Tunjungsari Muhammad Naufal Alzaky