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All Journal CoMPHI Journal : Community Medicine and Public Health of Indonesia Journal
Isbandiyah Isbandiyah
Universitas Muhammadiyah Malang
Health Professions Medicine & Pharmacology Nursing Public Health

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Potensi Ekstrak Bunga Telang (Clitoria ternatea) Sebagai Pencegah Acute Kidney Injury (AKI) Ersalita Rahmadhani Pratiwi; Sukma Oktavia Aulia Rahmandani; Achmad Rivaldy Ibrahim; Isbandiyah Isbandiyah
CoMPHI Journal: Community Medicine and Public Health of Indonesia Journal Vol. 1 No. 2 (2020): Oktober
Publisher : Perhimpunan Dokter Kedokteran Komunitas dan Kesehatan Masyarakat Indonesia (PDK3MI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (212.056 KB) | DOI: 10.37148/comphijournal.v1i2.16

Abstract

Introduction: Butterfly pea (Clitoria ternatea) is a vine that has various colors such as pink, light blue, white, and purple. This plant is commonly used as a food coloring and ornamental plants. Butterfly pea has pharmacological potential, among others, as high antioxidants. The antioxidants of the butterfly pea show much higher activity than other flowers. Antioxidants are substances that can prevent the occurrence of Acute Kidney Injury (AKI), which is currently increasing in incidence and mortality due to AKI reaching 23.9% in adults and 13.8% in children. Aim of study: This article aims to discuss the potential of butterfly pea extract (Clitoria ternatea) as a preventative for Acute Kidney Injury (AKI). Method: The research method used is the literature search technique on 20 articles from the Google Scholar database. Results and Discussion: The results of the literature search show that the butterfly pea (Clitoria ternatea) has antioxidant compounds that have the potential to prevent the occurrence of acute kidney injury (AKI). Butterfly pea extract has the potential to reduce levels of urea, serum creatinine, reduce levels of malondialdehyde (MDA) and increase levels of glutathione, catalase, and superoxide dismutase (SOD). The antioxidant activity of flavonoids and tannins in butterfly pea extract was found to have a nephroprotective effect against exposure to toxic substances. Conclusion: The conclusion from this literature search is that the antioxidant content contained in butterfly pea extract can be a good alternative as a nephroprotector to prevent AKI.
Pengaruh Gangguan Ritme Sirkadian Dengan Kejadian Diabetes Melitus Tipe 2 Andityo Sumbarwoto; Isbandiyah Isbandiyah; Halida Nelasari; Geovani Rarung
CoMPHI Journal: Community Medicine and Public Health of Indonesia Journal Vol. 3 No. 2 (2022): Oktober
Publisher : Perhimpunan Dokter Kedokteran Komunitas dan Kesehatan Masyarakat Indonesia (PDK3MI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37148/comphijournal.v3i2.103

Abstract

Globally, it is estimated that around 422 million adults had diabetes in 2014. Diabetics then have a higher risk of developing other diseases, such as: stroke and heart attack. Circadian rhythm disorders such as sleep disorders are one of the factors causing type 2 diabetes mellitus. This study isintended to increase knowledge and as a basis for further research on the effect of circadian misalignment in type 2 diabetes mellitus and to determine the effect of sleep disorders on type 2 diabetes. This research is a literature review with a database of articles on Google Scholar, PubMed, and Science Direct from 2016 to 2021 from national journals, and international journals indexed by Scopus and ISSN. Circadian misalignment discussed in this study is that sleep disorders affect the incidence of type 2diabetes mellitus. Lack of or little sleep will affect type 2 diabetes mellitus. This effect is mediated by a number of hormones such as melatonin, cortisol, leptin, and ghrelin. There is an effect of circadian misalignment on the incidence of type 2 diabetes mellitus.
Co-Authors Achmad Rivaldy Ibrahim Andityo Sumbarwoto Ersalita Rahmadhani Pratiwi Geovani Rarung Halida Nelasari Sukma Oktavia Aulia Rahmandani