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All Journal Jurnal Inovasi Farmasi Indonesia Pharmaceutical Sciences and Research (PSR)
Damayanti, Amitasari
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Decision Sciences, Operations Research & Management Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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Evaluation of Category I of Anti-tuberculosis Therapy in Intensive Phase Pulmonary TB by Conversion of Acid-Fast Bacilli Sputum Putra, Oki Nugraha; Damayanti, Amitasari; Nurrahman, Nani Wijayanti Dyah; Devi, Tsania; Aluf, Wildatul
Pharmaceutical Sciences and Research Vol. 6, No. 3
Publisher : UI Scholars Hub

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Abstract

Acid fast bacilli (AFB) sputum microscopy is used to diagnose tuberculosis (TB) and to evaluate the effectiveness of anti-tuberculosis drugs in TB eradication program. The AFB sputum microscopy should be performed before treatment, two months after intensive phase and four months after advance phase treatment. The aim of this study was to evaluate the sputum conversion rate of AFB in pulmonary TB patients who received category I of antituberculosis (anti-TB) drugs. Evaluation of sputum conversion was perfomed before initation of anti TB drugs and at the end of the intensive phase. This cohort prospective study was done from February to May, 2018. Nine pulmonary TB patients fulfilled the criteria during the study. This AFB sputum microscopy was evaluated by using Ziehl Neelsen and read by means of International Union Against Tuberculosis and Lung Disease (IUATLD) scale. Nine sputum smear positive were followed for two months. After two months (end of the intensive phase), the smear conversion rate was 100%. All patients received standard dose of anti-TB drugs in fix dose combination (FDC). It can be concluded that the sputum conversion of AFP in pulmonary TB patients who received category I of anti-TB was success at the second month of intensive phase.
Evaluasi Efektivitas Antibiotika Pada Pasien Ginjal Kronik Yang Menjalani Hemodialisa Di RSPAL dr.Ramelan Surabaya: Evaluation of Antibiotic Effectiveness in Chronic Kidney Disease Patients with Hemodialysis dr. Ramelan Hospital, Surabaya Damayanti, Amitasari; Risetyaningsih, Ayunanda; Kresnamurti, Angelica; Novela, Chandni Paramitha; Rizkadirianti , Nabila Indri Rizkadirianti
Jurnal Inovasi Farmasi Indonesia (JAFI) Vol. 7 No. 1 (2025): Volume 7 No 1 2025
Publisher : Universitas Kadiri

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30737/jafi.v7i1.6693

Abstract

Di Indonesia, tingkat penyakit ginjal kronik sebesar 0,38%, dan sekitar 60% penderita gagal ginjal memerlukan dialisis, menurut RISKESDAS 2018 Badan Penelitian dan Pengembangan Kesehatan penyakit ginjal kronik. Pasien dengan infeksi ginjal kronik harus segera diobati agar penyakit mereka tidak memperparah, yang dapat menyebabkan kematian. Antibiotik diberikan untuk memerangi infeksi bakteri. Tujuan dari penelitian ini untuk mengidentifikasi apakah pemberian antibiotik dapat mengurangi infeksi yang diderita pasien dengan melihat hasil lab pasien. Mereka juga ingin mengetahui apakah pemberian antibiotika telah memenuhi prinsip tepat diagnosis, pasien, antibiotik, dan regimen dosis yang tepat. Penelitian ini dilakukan sebagai penelitian kuantitatif observasional dengan retrospektif yang menggunakan data rekam medik pasien yang menderita ginjal kronik dan hemodialisa serta mendapatkan terapi antibiotik. Hasil menunjukkan bahwa 94,54% pasien tepat diagnosa, 91,51% tepat pasien, 64,84% tepat antibiotika, dan 21,81% tepat regimen dosis.
Co-Authors Aluf, Wildatul Devi, Tsania Kresnamurti, Angelica Novela, Chandni Paramitha Nurrahman, Nani Wijayanti Dyah Putra, Oki Nugraha Risetyaningsih, Ayunanda Rizkadirianti , Nabila Indri Rizkadirianti