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All Journal International Journal of Health and Pharmaceutical (IJHP)
Linda Chiuman
Program Study Master Of Biomedic Science Faculty Of Medicine Universitas Prima Indonesia Medan, North Sumatera, Indonesia
Nursing Public Health

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Testing Antioxidant And Antibacterial Activity Of Andaliman Fruit (Zanthoxylum Acanthopodium Dc.) Ethanol Extract With Abts Method (2,2'-Azino-Bis(3-Ethylbenz-Thiazoline-6-Sulfonic Acid) And Minimum Resistant Concentration Agung Adha Witasa Dewana; Tan Suyono; Linda Chiuman; Sahna Ferdinand Ginting
International Journal of Health and Pharmaceutical (IJHP) Vol. 2 No. 1 (2022): February 2022
Publisher : CV. Inara

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (254.853 KB) | DOI: 10.51601/ijhp.v2i1.35

Abstract

Antioxidants are chemical compounds that can donate one or more electrons to free radicals, so that these free radicals can be quenched. There are two sources of antioxidants, namely natural and synthetic antioxidants. Andaliman (Zanthoxylum acanthopodium DC.) is one of the many spice plants found in Toba Samosir and North Tapanuli Regencies, North Sumatra. Andaliman plants grow at an altitude of 1,500 m above sea level. Apart from North Sumatra. This research using method experimental research when collecting and processing andaliman fruit, making simplicia, making ethanol extracts and examining antioxidant activity tests using the ABTS free radical scavenging method (2,2'-azino-bis(3-ethylbenz-thiazoline-6-sulfonic acid) and antibacterial activity. using the minimum inhibitory concentration method. Testing the antioxidant activity of the ethanol extract of andaliman fruit with the ABTS method using a UV-VIS spectrophotometer with a wavelength of 734 nm. the regression equation (y = 0.4619 + 20.226) obtained an IC50 value of 64.4598 mg/mL which can be classified as a strong antioxidant activity. The results of the antibacterial activity test of the ethanol extract of the andaliman fruit showed that the extract had antibacterial activity in the moderate category at a concentration of 300 mg/ml with an inhibition zone of 10.
Test of Antioxidant And Antibacterial Activity of Ethanol Extract of Andaliman Fruit (Zanthoxylum Acanthopodium Dc.) With Dpph (1.1-Diphenyl-2-Picrylhydrazil) Trapping Method And Minimum Inhibitory Concentration Ira Syaputri; Ermi Girsang; Linda Chiuman
International Journal of Health and Pharmaceutical (IJHP) Vol. 2 No. 2 (2022): May 2022
Publisher : CV. Inara

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (249.591 KB) | DOI: 10.51601/ijhp.v2i2.36

Abstract

Utilization of bioavailability according to World Health Organization (WHO) records is very large, it is estimated that almost 80% of mankind, especially in developing countries, still use plants as medicinal ingredients to maintain their health (Nugraheni, 2007). Andaliman (Zanthoxylum acanthopodium DC.) which belongs to the Rutaceae tribe which is one of the plants known to the Batak community, is classified as a wild plant and is a typical plant of Province North Sumatra. The method used in this research is experimental research. The research included collecting and processing andaliman fruit, making simplicia, making ethanol extracts, and examining antioxidant activity tests using the DPPH free radical scavenging method (1,1-diphenyl-2-picrylhydrazil) and antibacterial activity using the minimum inhibitory concentration method. The results of the antibacterial activity test of the ethanolic extract of andaliman fruit showed that the extract had antibacterial activity in the moderate category at a concentration of 300 mg/ml with an inhibition zone of 10.17 mm for Staphylococcus aureus bacteria and a moderate category for Staphylococcus epidermidis bacteria with an inhibition zone of 10.80 mm. The ethanol extract of andaliman fruit can inhibit Staphylococcus aureus and Staphylococcus epidermidis, effective at a concentration of 300 mg/ml with inhibitory diameters of 10.17 mm and 10.80 mm, respectively.
Co-Authors Agung Adha Witasa Dewana Ermi Girsang Ira Syaputri Sahna Ferdinand Ginting Tan Suyono