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All Journal International Journal of Health Science & Medical Research
Nadya A R Bubakar
Hasanuddin University
Dentistry Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Veterinary

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CORRELATION BETWEEN THE DURATION OF ANTI-EPILEPTIC DRUGS THERAPY AND VITAMIN D LEVEL IN EPILEPTIC CHILDREN Hadia Anggriani Machmoed; Nadya A R Bubakar; Urfianty Urfianty; Idham Jaya Ganda
International Journal of Health Science & Medical Research Vol 2, No 1 (2023): February 2023
Publisher : UNG

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (369.93 KB) | DOI: 10.37905/ijhsmr.v2i1.14286

Abstract

Long-term use of antiepileptic drugs (AEDs) for epilepsy causes a decrease in vitamin D levels due to the activation of liver cytochrome P450 enzymes. The novelty of this study is due to researching about correlation between the duration of anti-epileptic drugs therapy and vitamin d level in epileptic children This cross-sectional study was conducted from October - December 2021in children with epilepsy aged 1 month to 18 years admitted to pediatric neurology polyclinic of DR Wahidin Sudirohusodo. They were divided into two groups: epileptic children receiving AEDs treatment ≤ 1 year and epileptic children receiving AEDs treatment 1 year. Statistical analysis showed no significant relationship between the duration of AEDs use and the incidence of vitamin D deficiency in children with epilepsy.Keywords: Vitamin D Deficiency; Antiepileptic Drugs; Epilepsy
Co-Authors Hadia Anggriani Machmoed Idham Jaya Ganda Urfianty Urfianty