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All Journal Makara Journal of Health Research
Mugada, Vinodkumar
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Association between sociodemographic factors and estrogen receptor-positive, progesterone receptor-positive breast cancer subtypes: A cross-sectional study Mugada, Vinodkumar; Kolakota, Raj Kiran; Mahato, Varsha
Makara Journal of Health Research Vol. 24, No. 2
Publisher : UI Scholars Hub

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Background: The presence of risk factors have a high risk of developing breast cancer. Our study aimed to find an association between sociodemographic factors and the risk of estrogen receptor (ER)-positive, progesterone receptor (PR)-positive breast cancer among women. Methods: A cross-sectional study was conducted on 200 women with breast cancer. Association between sociodemographic factors and hormone receptor subtypes of breast cancer was found using the Chi-square test. Multiple logistic regression analysis was used to know the strong predictors of hormone receptor subtypes. Results: The mean age was 50.08 (10.67) years. Comorbidities had a statistically significant association with ER-positive subtype (p = 0.007). Body mass index had a statistically significant association with PR-positive subtype (p = 0.042). Comorbidities was found to be the strong independent predictor for ER-positive (OR 2.28; 95% CI: 1.28–4.05, p = 0.003) and PR-positive subtypes (OR 1.78; 95% CI: 1.01–3.13, p = 0.03). Conclusion: We conclude that in our study, body mass index was associated with PR-positive subtype, and comorbidities were associated with ER-positive subtype of breast cancer among the women. Comorbidities remained to be a strong independent predictor of ER-positive and PR-positive subtypes of breast cancer.
Quality of Life of Pharmacy Students with Polycystic Ovarian Syndrome in South India: A Cross-Sectional Study Mugada, Vinodkumar; Mandarapu, Krishna Priya
Makara Journal of Health Research Vol. 25, No. 3
Publisher : UI Scholars Hub

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Background: One in five women in India suffers from polycystic ovarian syndrome (PCOS). In this study, we aimed to evaluate the quality of life of pharmacy students suffering from PCOS and provide awareness through counseling. Methods: A cross-sectional study was conducted on 103 students with PCOS for 6 months. The Polycystic Ovarian Syndrome Quality of Life (PCOSQ) questionnaire was used to determine the quality of life. Results: The prevalence of PCOS in our study was 39.5%. The mean age of the students was 21.1 (±1.8) years. The mean duration of the disorder was 17.8 (±13.0) months. More than three-quarters (77.6%) of them were under medications. Menstrual problems had a severe negative impact on the quality of life. In addition, emotion, body hair, weight gain, and infertility had a moderate impact on the quality of life. A significant association was observed among sleeping habits and infertility problems (p = 0.014), physical activity, weight (p = 0.032), and menstrual problems (p = 0.042). Conclusions: Menstrual problems have a significant impact on the quality of life of students with PCOS. Moreover, health science students must develop an awareness of prevalent noncommunicable diseases to help themselves and the society.
Co-Authors Kolakota, Raj Kiran Mahato, Varsha Mandarapu, Krishna Priya