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All Journal Makara Journal of Health Research
Yildiz, Nesibe
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Association Between Cigarette Smoking and Breast Milk Levels of Nesfatin-1, Irisin, and Oxidative Stress Markers Yildiz, Nesibe; Yilmaz, Adnan; Iskender, Hatice; Dokumacioglu, Eda
Makara Journal of Health Research Vol. 25, No. 3
Publisher : UI Scholars Hub

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Background: Breast milk is a very important functional food in the prevention of metabolic and chronic diseases. This study aimed to investigate the effects of smoking during pregnancy on the concentrations of nesfatin-1, irisin, and oxidative stress markers in breast milk. Methods: This study included two groups of 14 smoking and 14 nonsmoking mothers. Malondialdehyde (MDA) level and superoxide dismutase (SOD) activity were measured according to the spectrophotometric method in breast milk samples. Nesfatin and irisin levels were measured by enzyme-linked immunosorbent assay. Results: Levels of nesfatin-1 and MDA of the smoking group were significantly higher than those in the control group (p < 0.001). The SOD activity of the smoking group was significantly lower than that of the control group (p < 0.001). No significant difference was found in the breast milk irisin level between the study groups (p > 0.050). Conclusions: Cigarette smoking increases MDA level and decreases SOD activity in breast milk. Nesfatin-1 levels would increase in accordance with increased oxidative stress, and nesfatin-1 acts as a protective mechanism to limit oxidative damage.
Premenstrual Syndrome Levels and Eating Attitudes Among University Students Bahadur, Ceyda; Ergen, Dilara; Yildiz, Nesibe; Dokumacioglu, Eda
Makara Journal of Health Research Vol. 27, No. 2
Publisher : UI Scholars Hub

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Background: Premenstrual syndrome (PMS) is the combination of physical, behavioral, and psychological symptoms that characterize the week leading up to menstruation, and it can last for a few days. This study aimed to investigate irregular PMS, eating attitude behavior, and body mass index values among university students. Methods: The study sample consisted of 140 Artvin Coruh University students studying Nutrition and Dietetics. The study includes questions from three separate sections. The first section contains a sociodemographic characteristic form, the second section consists of the Premenstrual Syndrome Scale (PMSS), and the third section includes the 26-item Eating Attitude Test (EAT-26). Results: In this study, the mean total score for PMSS was 135 ± 38.3, and the mean total score for EAT-26 was 17.0 ± 10.8. Individuals with irregular sleep patterns experienced more severe PMS (p < 0.01) and a shorter daily sleep duration (p < 0.05). Conclusions: High percentages of nutrition and dietetics students in our study experienced PMS, and the incidence of eating disorders was low. The relationship between PMS and EAT-26 must be understood for the health and well-being of university students.
Association of Smoking with Total Oxidant and Antioxidant Levels in Breast Milk Yildiz, Nesibe; Yilmaz, Adnan
Makara Journal of Health Research Vol. 26, No. 3
Publisher : UI Scholars Hub

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Background: Breast milk is a natural food that contains all the fluids, energy, and nutrients necessary for the optimum growth and development of newborns. Smoking is a public health problem that has harmful effects on the mother and baby. This study aimed to examine the association of exposure to smoking with total oxidant status (TOS) and total antioxidant status (TAS) in breast milk. Methods: Healthy mothers without any health problems during their pregnancy and lactation periods were selected as subjects. Eighty-eight milk samples (44 in the smoking group and 44 in the nonsmoking group) were examined. TOS and TAS were analyzed using Rel Assay commercial kits. Results: TAS level was significantly lower in the smoking group than in the nonsmoking group (p < 0.05). TOS level was higher in the smoking group than in the nonsmoking group, although the difference was not statistically significant (p > 0.05). Oxidative stress index (OSI) was significantly higher in the smoking group than in the nonsmoking group (p < 0.05). Conclusions: Exposure to smoking was associated with low TAS and high OSI in breast milk.
Co-Authors Bahadur, Ceyda Dokumacioglu, Eda Ergen, Dilara Iskender, Hatice Yilmaz, Adnan