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All Journal Makara Journal of Health Research
Islam, Muhammed Mohibul
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Evaluation of Biochemical and Pathological Parameters at Different Doses of Cisplatin in Experimental Animal Model: Toxicological Study on an Antineoplastic Drug Sultana, Farhana; Islam, Muhammed Mohibul; Amin, Mohammad Nurul; Jahan, Nusrat; Kabir, Asma; Emran, Talha Bin; Sutradhar, Bibek Chandra; Banik, Sujan
Makara Journal of Health Research Vol. 26, No. 1
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Background: This study aimed to assess the effect of cisplatin-induced toxicities on biochemical and pathological parameters such as body, liver, and kidney weights, blood urea nitrogen (BUN), creatinine, alanine aminotransferase (ALT), and blood cells (RBCs and WBCs) in white Swiss albino mice. Methods: Cisplatin’s potential toxic effects on body, liver, and kidney weights were evaluated using standard laboratory methods. Blood biochemical levels such as BUN, creatinine, and ALT levels were determined by an auto-hemolyzer using commercial diagnostic kits. Blood cells (RBCs and WBCs) were counted under a microscope by a hemocytometer. Results: Cisplatin’s potential toxic effects on body, liver, and kidney weights were evaluated using standard laboratory methods. Blood biochemical levels such as BUN, creatinine, and ALT levels were determined by an auto-hemolyzer using commercial diagnostic kits. Blood cells (RBCs and WBCs) were counted under a microscope by a hemocytometer. Conclusions: This study suggested to increase caution when using cisplatin, particularly at high doses. Further investigation shall be performed to minimize its toxic effect and optimize its use.
Cross-Sectional Study on Overweight and Obesity Associated with Fast-Food Consumption in Bangladesh Sultana, Farhana; Siddiqui, Shafayet Ahmed; Islam, Md. Ashraful; Al Muktadir, Mohammad Hamid; Millat, Md. Shalahuddin; Islam, Muhammed Mohibul; Tareq, Abu Montakim; Afroz, Nahida; Rahman, Mahabuba; Amin, Mohammad Nurul; Emran, Talha Bin
Makara Journal of Health Research Vol. 26, No. 2
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Background: This study aimed to investigate the risk factors and status of fast-food consumption among students in Bangladesh. Methods: This cross-sectional study was conducted from March to November 2020. A total of 654 samples were collected from several schools, colleges, and universities during this study period. Results: About 60.1% and 39.9% of the students were male and female, respectively. Of the students, 53.1% considered fast food as unhealthy (p < 0.001), but only 47.7% were leading a sedentary lifestyle. A significant outcome of overweight and pre-obesity was observed for student institutions, consumption frequency, daily fast-food consumption, and sedentary lifestyle (p < 0.001). In addition, positive association was observed for fast-food consumption more than three times and less than three times per week (OR and 95% CI: 11.13 [7.52–16.47], p < 0.001), higher social class and lower class (OR and 95% CI: 2.18 [1.31–3.62], p = 0.003), fast food preference and other foods (OR and 95% CI: 1.55 [1.11–2.15], p = 0.009), and sedentary and heavily active lifestyle (OR and 95% CI: 5.71 [2.02–16.10], p = 0.001) using logistic regression. Conclusions: Overweight and obesity are serious public health concerns, which are highly associated with fast-food consumption along with lifestyle, economy, and fast-food preference among students in Dhaka City, Bangladesh.
Assessment of Sociodemographic Status, Self-awareness, and Risk Factors Affecting Patients with Prediabetes in Bangladesh: Cross-sectional Study Sultana, Farhana; Islam, Muhammed Mohibul; Das, Aparajita; Rahman, Md Hasan Shahriar; Pia, Nandita Islam; Mahmud, Md Kayes; Mostaq, Md. Saqline; Saadullah, Saadullah; Hossain, Md. Saddam; Fakir, Saikat; Amin, Mohammad Nurul
Makara Journal of Health Research Vol. 28, No. 1
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Background: Poor glycemic control and high diabetes and prediabetes incidence are influenced by socioeconomic disparity. Raising awareness and ensuring that people with prediabetes are receiving medication, maintaining their glycemic control, and getting the proper care they need despite their socioeconomic situation are crucial in the fight against diabetes. This study aims to assess the sociodemographic status, self-awareness, and risk factors associated with prediabetes in Bangladesh. Methods: A cross-sectional survey was carried out among 500 participants aged >18 years to evaluate and summarize their demographic data, socioeconomic status, and responses to various questionnaires about their conditions related to prediabetes and their awareness of this condition. Results: Analysis of factors revealed that 41% and 39% of the participants had first- and second-degree relatives with diabetes, respectively. Meanwhile, 36% of the participants maintain physical activities, 30% prefer sweetened beverages, and 29% have high blood pressure. The participants were aware of different statements related to diabetes, such as how lifestyle modification and awareness can help people with prediabetes. Conclusions: This study provided insights into the underlying factors related to prediabetes and enabled us to identify the prediabetes conditions unknown to people in Bangladesh.
Knowledge, Awareness, and Perceived Barriers Regarding Cervical Cancer Screening Among Bangladeshi Women Suffering from Cervical Cancer: A Cross-sectional Study Islam, Muhammed Mohibul; Sultana, Farhana; Rahman, Md Hasan Shahriar; Pia, Nandita Islam; Hasibuzzaman, Md. Al; Ahmed, Arman; Hasan, Mohammed Shamim; Mahmud, Md Kayes; Akter, Rabeya; Mostaq, Md. Saqline; Amin, Mohammad Nurul
Makara Journal of Health Research Vol. 27, No. 2
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Background: This study aimed to evaluate the knowledge, awareness, and perceived barriers regarding cervical cancer screening among women in Bangladesh. Methods: A hospital-based survey was conducted from January to April 2021 among 200 female participants. Statistical analysis of this study was performed by using Stata 13 (StataCorp LP, 4905 Lakeway Drive, College Station, TX 77845, USA), where Chi-square test was used for the determination of the correlation among different variables. Results: Among the participants, 86.5% were rural residents, 96% were married, 87.5% were housewives, 47% were uneducated, and 93.5% lived on a husband’s income. Moreover, 84.5% hadn’t any family history of cancer, 91.5% had no knowledge about cervical self-examination, 74.5% and 61.5% never heard of screening programs and cervical cancer, respectively (p < 0.05). In addition, 23.5% knew that early sexual activity was a risk factor for cervical cancer. Again, the outcome of ideas about other people’s thinking (6%), the stigma of cancer diagnosis (15%), difficulty talking with doctors (5%), poor knowledge (12.5%), and fear of physicians and examiners (5%) were statistically significant (p < 0.05). Conclusions: This study revealed that most female respondents lack knowledge and awareness regarding cervical cancer. To improve this situation, appropriate and socially acceptable awareness programs are necessary.
Co-Authors Ahmed, Arman Akter, Rabeya Al Muktadir, Mohammad Hamid Amin, Mohammad Nurul Banik, Sujan Das, Aparajita Emran, Talha Bin Fakir, Saikat Hasan, Mohammed Shamim Hasibuzzaman, Md. Al Hossain, Md. Saddam Islam, Md. Ashraful Jahan, Nusrat Kabir, Asma Mahmud, Md Kayes Millat, Md. Shalahuddin Mostaq, Md. Saqline Nahida Afroz Pia, Nandita Islam Rahman, Mahabuba Rahman, Md Hasan Shahriar Saadullah, Saadullah Siddiqui, Shafayet Ahmed Sultana, Farhana Sutradhar, Bibek Chandra Tareq, Abu Montakim