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All Journal Journal of Pain, Vertigo and Headache
Hanik Hidayati
Neurology Department, Medical Faculty, Airlangga University, Dr. Soetomo General Hospital, Surabaya, Indonesia
Neuroscience

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PARACETAMOL, MIGRAINE, AND MEDICATION OVERUSE HEADACHE (MOH) Hanik Hidayati; Anung Kustriyani
Journal of Pain, Headache and Vertigo Vol. 1 No. 2 (2020): September
Publisher : Journal of Pain, Headache and Vertigo

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (242.994 KB) | DOI: 10.21776/ub.jphv.2020.001.02.5

Abstract

Paracetamol is a nonopioid synthesized p-aminophenol derivative that used as an antipyretic and an analgesic. Paracetamol is an over the counter medicine. 15.6% of migraine patients took paracetamol for headache relief. In migraine, paracetamol is used long term. This triggers paracetamol to cause Medication Overuse Headache (MOH). Animal studies associated paracetamol induced MOH based on pathophysiology migrenes. There three mechanism underline MOH include effect to korteks cerebral, effect to system trigeminal nociception, and effect to central modulating systems.
PARACETAMOL, MIGRAINE, AND MEDICATION OVERUSE HEADACHE (MOH) Hanik Hidayati; Anung Kustriyani
Journal of Pain, Headache and Vertigo Vol. 1 No. 2 (2020): September
Publisher : Journal of Pain, Headache and Vertigo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.jphv.2020.001.02.5

Abstract

Paracetamol is a nonopioid synthesized p-aminophenol derivative that used as an antipyretic and an analgesic. Paracetamol is an over the counter medicine. 15.6% of migraine patients took paracetamol for headache relief. In migraine, paracetamol is used long term. This triggers paracetamol to cause Medication Overuse Headache (MOH). Animal studies associated paracetamol induced MOH based on pathophysiology migrenes. There three mechanism underline MOH include effect to korteks cerebral, effect to system trigeminal nociception, and effect to central modulating systems.
Co-Authors Anung Kustriyani