Article Per Year (5 Year)
p-Index From 2021 - 2026
0
P-Index
This Author published in this journals
All Journal ISM (Intisari Sains Medis) : Jurnal Kedokteran
Hermawan Hermawan
Program Pendidikan Dokter Spesialis Ilmu Patologi Klinik FK UNHAS / RSUP Dr. Wahidin Sudirohusodo, Makassar, Indonesia
Biochemistry, Genetics & Molecular Biology Medicine & Pharmacology

Published : 1 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 1 Documents
Search

 1 
Analisis nilai diagnostik C-reactive protein pada pasien pediatrik dengan apendisitis di RSUP Dr. Wahidin Sudirohusodo, Makassar, Indonesia Hermawan Hermawan; Darwati Muhadi; Ibrahim Abdul Samad
Intisari Sains Medis Vol. 10 No. 2 (2019): (Available online: 1 August 2019)
Publisher : DiscoverSys Inc.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (409.05 KB) | DOI: 10.15562/ism.v10i2.417

Abstract

Background : Acute appendicitis associated with acute phase reaction is the most prevalent disease which requires emergency surgery. Its delayed diagnosis and unnecessarily performed appendectomies lead to numerous complications. In our study, we aimed to detect the role of C-reactive protein (CRP) in the exclusion of acute and complicated appendicitis and diagnostic accuracy in pediatric age group.Methods : A retrospective analytic observational study with cross-sectional design was performed on 69 children with definitive appendicitis. Appendectomized patient groups were constructed based on the results of histopathological evaluation. The area under a receiver operating characteristic (ROC) curve (AUC) was performed to examine diagnostic accuracy.Results : Based on cut-off values of ≥ 22,6 mg/dL for CRP level, diagnostic parameters were as follow : sensitivity 97,4%, specificity 80,0%, PPV 97,4%, NPV 80,0%, and diagnostic accuracy 89,9%. AUC values were 0,98 (95% CI 0,96 – 9,99) for CRP.Conclusion : For complicated appendicitis, CRP has the highest degress of diagnostic accuracy. The diagnosis appendicitis should be made primarily based on clinical examination, and obviously more specific and systemic inflammatory markers are needed. Cut-off values of CRP ≥ 22,6 mg/dL provides discrimination values for complicated appendicitis.
Co-Authors Darwati Muhadi Ibrahim Abdul Samad