Article Per Year (5 Year)
p-Index From 2020 - 2025
0.23
P-Index
This Author published in this journals
All Journal ISM (Intisari Sains Medis) : Jurnal Kedokteran
Eunike Cahyaningsih
Ophthalmology Department, Prof. Dr. W.Z. Yohanes General Hospital, Kupang, East Nusa Tenggara, Indonesia
Biochemistry, Genetics & Molecular Biology Medicine & Pharmacology

Published : 1 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 1 Documents
Search

 1 
The potential role of vitamin D supplementation in the treatment of Dry Eye Disease (DED): a systematic review Tiara Alexander; Eunike Cahyaningsih
Intisari Sains Medis Vol. 13 No. 1 (2022): (Available Online : 1 April 2022)
Publisher : DiscoverSys Inc.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (655.239 KB) | DOI: 10.15562/ism.v13i1.1250

Abstract

Background: Dry Eye Disease (DED) is a prevalent condition that involves instability, increased osmolarity, and inflammation of the tear film and ocular surface. Vitamin D is known for its anti-inflammatory properties. Association between vitamin D deficiency and increased incidence of DED has been suggested. However, no study currently exists that systematically reviews the potential role of vitamin D as a treatment for DED. Methods: The literature search was performed on December 2021 through PubMed, Scopus, ProQuest, EBSCOhost, ScienceDirect, dan Cochrane Library using the relevant keywords. The risk of bias was assessed using the Cochrane Risk of Bias tool, ROBINS-I tools, and the Newcastle-Ottawa Scale. Results: A total of 700 articles were found, 6 of which were considered relevant based on PRISMA protocol. The included articles consist of 2 case controls, a randomized interventional study, and 3 observational studies. Vitamin D supplementation improved tear stability, symptoms of dry eye disease, and serum vitamin D level affected the efficacy of topical therapy for DED. Conclusion: Despite this beneficial finding, serum vitamin D level does not significantly correlate with DED symptoms which the multifactorial nature of the disease might cause.
Co-Authors Tiara Alexander