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All Journal Trends in Infection and Global Health
Irfan Ullah
Kabir Medical College, Gandhara University, Peshawar, Pakistan
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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Irrational use of azithromycin in typhoid endemic areas: A challenge on multidrug-resistant typhoid treatment Irfan Ullah; Kiran Shafiq Khan; Qasim Mehmood; Muhammad Junaid Tahir; Muhammad Irfan Malik; Ali Ahmed; Muhammad Usman Munir
Trends in Infection and Global Health Vol 1, No 2 (2021): December 2021
Publisher : School of Medicine, Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24815/tigh.v1i2.23580

Abstract

Typhoid is a food-borne fatal disease caused by Salmonella typhi. It causes inflammation of the intestine, resulting in diarrhoea, fever, headache, cough, and muscle pain. Improved hygiene has resulted in a marked decline in typhoid fever cases in many developed countries. However, significant typhoid cases emerge in low and middle-income countries annually, including Pakistan. Typhoid fever accounts for a larger percentage of acute febrile illnesses in Pakistan. Azithromycin is the only effective drug used in multidrug-resistant typhoid. The emergence of drug resistance typhoid has been of more significant concern in recent years due to its irrational use of azithromycin. It is considered the last antibiotic to eradicate multidrug-resistant typhoid fever from Pakistan. In this article, we express our concern of the irrational use of azithromycin in Pakistan and its effect on typhoid in the country.
A rare case of varicella zoster virus encephalitis in a 16 years old unvaccinated girl Abdul Wali Khan; Abad Khan; Muhammad Ishaq; Irfan Ullah; Marhami Fahriani
Trends in Infection and Global Health Vol 1, No 1 (2021): June 2021
Publisher : School of Medicine, Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24815/tigh.v1i1.20362

Abstract

We reported a 16-year-old girl, with diffuse vesicular rashes all over the body, presented to the emergency department with altered mental status, irritability, persistent fever and one episode of a generalized tonic-clonic seizure. After thorough evaluation and investigations, the case was a varicella zoster-associated encephalitis in an unvaccinated patient. Appropriate treatment was initiated, the patient was then shifted to the critical care and subsequently discharged with no sequelae. Early diagnosis and treatment should be emphasized as they play an important role in the clinical outcome of chickenpox-associated encephalitis.
Co-Authors Abad Khan Abdul Wali Khan Ali Ahmed Kiran Shafiq Khan Marhami Fahriani Muhammad Irfan Malik Muhammad Ishaq Muhammad Junaid Tahir Muhammad Usman Munir Qasim Mehmood