Article Per Year (5 Year)
p-Index From 2021 - 2026
0.23
P-Index
This Author published in this journals
All Journal Jurnal Biomedika dan Kesehatan JUARA: JURNAL WAHANA ABDIMAS SEJAHTERA
Rina K Kusumaratna
Unknown Affiliation
Humanities Biochemistry, Genetics & Molecular Biology Education Engineering Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Public Health Social Sciences

Published : 2 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 2 Documents
Search

 1 
PELIBATAN MASYARAKAT DENGAN PEMBERDAYAAN WARGA UNTUK MENCEGAH POTENSI PENYAKIT LEPTOSPIROSIS KELURAHAN KEBAGUSAN, JAKARTA SELATAN Rina K Kusumaratna; BS Pribadi; DA Itami
JUARA: Jurnal Wahana Abdimas Sejahtera Volume 2, Nomor 2, Juli 2021
Publisher : Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1463.532 KB) | DOI: 10.25105/juara.v2i2.9804

Abstract

Leptospirosis is a zoonotic disease in sub-tropical and tropical climates, could develop into epidemics in both rural and urban areas. Leptospirosis usually occurs after the patient comes into after contact with flood. In the last 5 years the case of disease has increased in DKI Jakarta, as well as in the Kebagusan sub-district of South Jakarta which consists of 8 RWs, from 2017-2019 there were found 5 cases and  potential for an epidemic at surrounding of neighborhood. Therefore, community engagement has a vital role to improve a disease prevention needs,  thus those  community are able to do an independently prevention activity or groups in their habitant. The activity begins with conducting an environment observational, advocacy and coordination, education and training for cadres, public facilities and infrastructure handling workers (PPSU) and residents representative of 3 RWs. From education results activities carried out on 36 targets, the pre-posttest on educated intervention was significant (p=0.000, T-paired test). It’s mean that the target increase their knowledge and understands the potential and risk of leptospirosis disease carried by rats for individual health and community after interventions. Empowerment can be started from the family level to maintain the cleanliness of the home environment as a form of personal responsibility and an important key to break the chain of leptospirosis transmission caused by rats
Paradigma baru penggunaan statin: efek kardioprotektif atau penyebab onset baru diabetes melitus? Gede Bangun Sudrajad; Armi Setia Kusuma; Rina K Kusumaratna
Jurnal Biomedika dan Kesehatan Vol 3 No 2 (2020)
Publisher : Fakultas Kedokteran Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/JBiomedKes.2020.v3.101-108

Abstract

3-Hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors atau yang biasa disebut sebagai statin, merupakan obat yang sudah digunakan sejak 30 tahun silam dan merupakan salah satu obat yang paling sering digunakan untuk terapi dislipidemia. Menurut hasil terbaru dari banyak studi observasional, randomized controlled trials (RCTs) dan meta-analyses telah mengonfirmasi adanya korelasi kejadian diabetes melitus (new-onset diabetes mellitus/NODM) setelah inisiasi penggunaan statin. Mekanisme spesifik terkait pengaruh statin terhadap kejadian diabetes melitus masih belum sepenuhnya dipahami, namun gangguan fungsi sel beta pankreas melalui calcium channel blockade, berkurangnya sensitivitas jaringan terhadap insulin akibat berkurangnya ekspresi GLUT 4, rendahnya kadar adiponektin dan mungkin mekanisme lainnya diduga menjadi faktor pencetus NODM. Sebagaimana yang kita tahu, statin digunakan dalam terapi dislipidemia serta pencegahan baik primer maupun sekunder terhadap kejadian penyakit kardiovaskular melalui efek pleiotropiknya. Namun, dengan adanya keterkaitan kejadian NODM maka makna protektif penggunaan statin menjadi berkurang. Pada artikel ini akan dibahas mengenai kemungkinan mekanisme statin terkait kejadian NODM dan makna penggunaanya sebagai pencegahan penyakit kardiovaskular.
Co-Authors Armi Setia Kusuma BS Pribadi DA Itami Gede Bangun Sudrajad