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Amri Junus
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Grading Tumor Pasien Adenocarcinoma Colorectal di RS Dr. Hasan Sadikin Bandung Tahun 2015 Farah Faza Aulia; Meike Rachmawati; Amri Junus
Bandung Conference Series: Medical Science Vol. 2 No. 1 (2022): Bandung Conference Series: Medical Science
Publisher : UNISBA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/bcsms.v2i1.955

Abstract

Abstract.Colorectal adenocarcinoma is the third most common malignancy case in the world after lung and breast cancer with an incidence of 10.2%. In Asia, the incidence of colorectal adenocarcinoma was 957,896 cases (50.8%) with a very high mortality rate at 461,422 cases (52,4%) in 2018. Colorectal adenocarcinoma ranked third for the most common cancer in Indonesia. The pathological prognostic factors of colorectal adenocarcinoma consist of site, size, degree of penetration, lymph node and distant metastasis, histopathological variants, tumor differentiation grading, and lymphovascular invasion. This study aimed to determine the tumor differentiation grading characteristics of colorectal adenocarcinoma patients at Dr. Hasan Sadikin Hospital Bandung. The method used in this study was a cross-sectional descriptive analysis using medical records of colorectal adenocarcinoma patients obtained from the Department of Pathology Anatomy of Dr. Hasan Sadikin Hospital Bandung. 64 cases that met the inclusion criteria were found. This study showed that the proportion of moderately differentiated tumor cases (54%) was slightly more significant than well-differentiated ones (46%) and there was no patient with poorly differentiated tumor. It may be caused by the most common molecular pathway of colorectal adenocarcinoma being chromosomal instability which tend to have better tumor grading than other pathways. This study has some similarities and differences with the previous studies. In conclusion, most colorectal adenocarcinoma patients have moderately differentiated tumor grading. Abstrak. Adenocarcinoma colorectal merupakan kasus keganasan ketiga terbanyak di dunia setelah kanker paru dan payudara dengan angka kejadian 10,2%. Di Asia, insidensi adenocarcinoma colorectal adalah 957.896 kasus (50,8%) dengan angka kematian yang sangat tinggi yaitu 461.422 kasus (52,4%) pada tahun 2018. Adenocarcinoma colorectal menempati urutan ketiga kanker terbanyak di Indonesia. Faktor prognostik patologis adenocarcinoma colorectal terdiri dari lokasi, ukuran, derajat penetrasi, metastasis kelenjar getah bening, metastasis jauh, varian histopatologi, grading diferensiasi tumor, dan invasi limfovaskular. Penelitian ini bertujuan untuk mengetahui gambaran grading diferensiasi tumor pasien adenocarcinoma colorectal di RS Dr. Hasan Sadikin Bandung. Metode penelitian ini adalah analisis deskriptif potong lintang menggunakan rekam medis pasien adenocarcinoma colorectal yang diperoleh dari Bagian Patologi Anatomi RS Dr. Hasan Sadikin Bandung. Pada penelitian ini ditemukan 64 kasus yang memenuhi kriteria inklusi. Studi ini menunjukkan proporsi kasus tumor berdiferensiasi sedang (54%) sedikit lebih besar dibandingkan kasus tumor berdiferensiasi baik (46%) dan tidak ditemukan kasus dengan tumor diferensiasi buruk. Hal ini dapat dipengaruhi oleh jalur molekuler yang sering terjadi pada adenocarcinoma colorectal merupakan ketidakstabilan kromosom (CIN) yang cenderung memiliki derajat diferensiasi tumor yang lebih baik dibanding dengan jalur molekuler lain. Hasil penelitian ini memiliki hasil yang serupa dan berbeda dengan penelitian-penelitian sebelumnya. Kesimpulannya, sebagian besar pasien adenocarcinoma colorectal memiliki grading tumor berdiferensiasi sedang.
Hubungan Fisioterapi dengan Kualitas Hidup Pasien Osteoarthritis Lutut di RSUD dr. Soekardjo Kota Tasikmalaya Periode Maret-Agustus 2022 Halida Nur Azizah; Meta Maulida Damayanti; Amri Junus
Bandung Conference Series: Medical Science Vol. 3 No. 1 (2023): Bandung Conference Series: Medical Science
Publisher : UNISBA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/bcsms.v3i1.6302

Abstract

Abstract. Knee Osteoarthritis (OA) is a chronic musculoskeletal disorder, the worldwide’s major cause of pain and disability. This disease does not only have an impact on the physical, but affects other aspects such as mental, emotional, and social, so that it can ultimately reduce the quality of life of the knee OA patients. One of the treatment options that can be done is physiotherapy, with one of the goals is to improve the quality of life. The purpose of this research is to analyze the relationships between physiotherapy and quality of life of the knee OA patients in RSUD dr Soekardjo Tasikmalaya City. This research was conducted with analytic observational methods by cross-sectional approach. This research was conducted at RSUD dr Soekardjo Tasikmalaya City on 55 outpatients for the period March–August 2022 who were selected consecutively. The results of the univariate statistical test showed that 22 patients had physiotherapy and 33 patients did not have physiotherapy with the characteristics of 65% were female and 42% were aged ≥ 60 years. Patients filled out the SF-36 quality of life questionnaire, then bivariate analysis was performed with SPSS via the chi-square test. The results of the bivariate analysis showed that there was a significant relationship between physiotherapy and the quality of life of patients with knee OA at RSUD dr. Soekardjo Tasikmalaya City (P=0.001). The conclusion of this research is that physiotherapy is related to the quality of life of patients with knee OA. Keywords: Knee Osteoarthritis, Physiotherapy, Quality of Life. Abstrak. Osteoarthritis (OA) lutut adalah gangguan muskuloskeletal kronis yang menjadi penyebab utama nyeri dan disabilitas di seluruh dunia. Penyakit ini tidak hanya berdampak pada fisik, tetapi memengaruhi aspek lain seperti mental, emosional, dan sosial, sehingga akhirnya dapat menurunkan kualitas hidup penderita OA lutut. Salah satu pilihan terapi yang dapat dilakukan adalah fisioterapi, dengan salah satu tujuannya untuk meningkatkan kualitas hidup. Tujuan penelitian ini adalah menganalisis hubungan fisioterapi dengan kualitas hidup penderita OA lutut di RSUD dr. Soekardjo Kota Tasikmalaya. Penelitian ini dilakukan dengan metode observasional analitik menggunakan pendekatan cross-sectional. Penelitian ini dilakukan di RSUD dr. Soekardjo Kota Tasikmalaya pada 55 pasien rawat jalan periode Maret–Agustus 2022 yang dipilih secara consecutive. Hasil uji statistik univariat didapatkan 22 pasien melakukan fisioterapi dan 33 pasien tidak melakukan fisioterapi dengan karakteristik 65% perempuan dan 42% berusia ≥ 60 tahun. Pasien mengisi kuesioner kualitas hidup SF-36, kemudian dilakukan analisis bivariat dengan SPSS melalui uji chi-square. Hasil analisis bivariat menunjukkan terdapat hubungan bermakna antara fisioterapi dengan kualitas hidup penderita OA lutut di RSUD dr. Soekardjo Kota Tasikmalaya (P=0,001). Simpulan dari penelitian ini adalah fisioterapi berhubungan dengan kualitas hidup penderita OA lutut. Kata Kunci: Fisioterapi, Kualitas Hidup, Osteoarthritis Lutut.
Co-Authors Farah Faza Aulia Halida Nur Azizah Meike Rachmawati Meta Maulida Damayanti