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All Journal Al-Iqra Medical Journal : Jurnal Berkala Ilmiah Kedokteran Bali Dermatology Venereology and Aesthetic Journal
I Made Birawan
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Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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THE SELECTION OF MOISTURIZER FOR TREATMENT OF ATOPIC DERMATITIS Betsy Yosia Nadeak; I Made Birawan
Al-Iqra Medical Journal : Jurnal Berkala Ilmiah Kedokteran Vol 5, No 1 (2022): ILMU KEDOKTERAN
Publisher : Journal Medical Universitas muhammadiyah Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26618/aimj.v5i1.7690

Abstract

Atopic Dermatitis (AD) is a chronic inflammatory skin disease that is followed by itching, and affects certain part of a body, especially in the face of  infants (infantile phase) and flexural extremities part (in childhood). The etiology of AD is multifactorial such as skin barrier defects, genetics, immune dysregulation, and environment. Atopic Dermatitis management includes skincare and prevention of recurrence. Moisturizers have been shown have an important role in preventing inflammation of the skin, repairing the skin barrier, and also routine use of moisturizer can reduce the amount of topical corticosteroids used. Currently, the use of moisturizers is one of the standard treatments in AD. This paper will explain the role and formulation of moisturizers so that it can help health workers in determining the choice of moisturizer in AD.
Steroid-induced diabetes mellitus in pemphigus vulgaris patient at Bali Mandara Hospital: a case report Felicia Aviana; I Made Birawan
Bali Dermatology Venereology and Aesthetic Journal BDVJ - Vol. 4 No. 2 (December 2021)
Publisher : Explorer Front

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51559/8vc5nd62

Abstract

Background: Pemphigus vulgaris (PV) is a blistering autoimmune disease of the skin and mucous membranes defined histologically by intraepidermal blister due to acantholysis. Systemic corticosteroids and immunosuppressive agents had greatly improved the prognosis of pemphigus. However, steroid use often leads to metabolic complications, such as diabetes mellitus. This case report describes steroid-induced diabetes mellitus in PV, where the side effect of long-term high dosages steroid used and the method to manage it can be used as a study case. Case report: A 31-year-old man complained of new blisters from almost the entire body. He had a history of PV 1 year ago and no history of diabetes mellitus in the patient or family. He had a medication history of methylprednisolone 8 mg every 8 hours. Dermatological status showed erythema macules, extensive erosion almost on the entire body, the Nikolsky sign (+), and the Asboe-Hansen sign (+). Blood laboratory result: random blood glucose 451 mg/dl, HbA1c 12.3%. Histopathological examination: suprabasal blister, in which the basal cells still attached to the basement membrane show a “tombstone” appearance. The diagnosis was steroid-induced diabetes in pemphigus vulgaris. He was treated with steroids and insulin. Conclusion: Steroid use in PV treatment can lead to metabolic complications, such as diabetes mellitus. Regularly monitoring is needed to prevent complications due to steroid use.
Co-Authors Betsy Yosia Nadeak Felicia Aviana