Dianli Fitriani
Department of Anatomical Pathology, Faculty of Medicine, Universitas Sriwijaya/Dr. Mohammad Hoesin General Hospital, Palembang, Indonesia

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Overview of COVID-19 Infection Manifestation in Neuropsychiatry Aspect Dianli Fitriani
Open Access Indonesian Journal of Medical Reviews Vol. 1 No. 3 (2021): Open Access Indonesian Journal of Medical Reviews
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/oaijmr.v1i3.40

Abstract

At the end of 2019, the coronavirus infection pandemic shocked the world. This virus began with reports of infections in the Wuhan area, China. The death rate from COVID-19 infection can reach 3%; however, the mortality rate in critically ill patients with COVID-19 infection is much higher, reaching 61.5%. This study was aimed to summarize the neuropsychiatric impact and neuropathological mechanisms of COVID-19 infection. The primary manifestation of COVID-19 infection is respiratory tract infection. Coronavirus can penetrate the central nervous system and cerebrospinal fluid in less than a week. Histopathological examination of the brain of the deceased COVID-19-19 showed the potential for SARS-CoV-2 to infect the central nervous system (CNS). Neuroinflammation can also damage blood brain barrier. Several patients treated with COVID-19-19 infection exhibited confusion and agitation without respiratory symptoms or other signs of infection. The COVID-19 pandemic not only directly impacts infected individuals but has also caused a new wave of psychological stress in society.