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p-Index From 2021 - 2026
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This Author published in this journals
All Journal Indonesian Journal of Science and Technology Pharmacon: Jurnal Farmasi Indonesia
Nonni Soraya Sambudi
Universitas Pertamina
Computer Science & IT Environmental Science Health Professions Medicine & Pharmacology

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Modification of Kaolin with Carbon Quantum Dots as Composite for Methylene Blue Removal: Literature Review and Experiment Nonni Soraya Sambudi; Yuvan Sithambaran; Khee Chung Hui; Muhammad Wahyu Nugraha; Norashikin Ahmad Kamal; Noorfidza Yub Harun; Suriati Sufian
Indonesian Journal of Science and Technology Vol 7, No 2 (2022): IJOST: VOLUME 7, ISSUE 2, September 2022
Publisher : Universitas Pendidikan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.17509/ijost.v7i2.50810

Abstract

The modification of kaolin with nano-size fillers has exhibited excellent performance in the adsorption process. Carbon quantum dots (CQDs) are the new generation of nanoparticles that have attracted interest for their utilization as modifiers. In this study, a composite of metakaolin(MK)/CQDs was synthesized and tested for methylene blue (MB) removal. The heating and acid-alkali treatment of kaolin transformed it into MK. The interaction between MK and CQDs was analyzed using XPS to detect the binding of pyridic NH2 and C-N. By loading CQDs into the kaolin matrix, the surface area was improved and the removal of MB increased. For a lower MB concentration at 5 ppm, the removal efficiency could reach 96%. The composite exhibited good regeneration through the recyclability test.
Advances in Antibiotic-Loaded Nanofibers for the Treatment of Bone Infections: A Review Teguh Imanto; Nonni Soraya Sambudi; Khadijah Zai; Teuku Nanda Saifullah Sulaiman
Pharmacon: Jurnal Farmasi Indonesia Vol. 21 No. 2 (2024)
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/pharmacon.v21i2.6986

Abstract

Antibiotic-loaded nanofiber-based drug delivery systems represent a novel approach to treating complex bone infections, particularly osteomyelitis caused by antibiotic-resistant bacteria such as Methicillin-resistant Staphylococcus aureus (MRSA). These systems offer localized, sustained drug release, significantly reducing systemic side effects and mitigating the development of antibiotic resistance. This review evaluates advancements in electrospun nanofibers with biodegradable polymers like Poly(lactic-co-glycolic acid) (PLGA) and Polycaprolactone (PCL), which ensure controlled drug release while supporting bone regeneration. A systematic search using PRISMA guidelines across ScienceDirect and ACS Publication databases (2020-2024) identified 42 relevant studies. The inclusion of bioactive agents such as hydroxyapatite in nanofibers was found to enhance antibacterial properties and accelerate tissue regeneration. The review demonstrates that antibiotic-loaded nanofibers offer a promising, targeted therapeutic alternative to conventional treatments, particularly for osteomyelitis and similar challenging bone infections. Future research directions will focus on optimizing nanofiber compositions and functionalities to better meet clinical needs, ensuring more efficient and personalized management of severe bone infections.
Co-Authors Khadijah Zai Khee Chung Hui Muhammad Wahyu Nugraha Noorfidza Yub Harun Norashikin Ahmad Kamal Suriati Sufian Teguh Imanto Teuku Nanda Saifullah Sulaiman Yuvan Sithambaran