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All Journal JURNAL KIMIA SAINS DAN APLIKASI
Pri Iswati Utami
Department of Pharmaceutical Chemistry,Faculty of Pharmacy, Universitas Muhammadiyah Purwokerto, Purwokerto, 53182|Universitas Muhammadiyah Purwokerto|Indonesia
Chemical Engineering, Chemistry & Bioengineering Chemistry Engineering

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Determination of Antihistamine in Tablets Preparation by Fluorescence Quenching Method Aditya Singgih Raharjo; Asmiyenti Djaliasrin Djalil; Pri Iswati Utami
Jurnal Kimia Sains dan Aplikasi Vol 25, No 7 (2022): Volume 25 Issue 7 Year 2022
Publisher : Chemistry Department, Faculty of Sciences and Mathematics, Diponegoro University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/jksa.25.7.231-234

Abstract

The fluorescence properties of complexes of dexchlorpheniramine maleate (DXC) and erythrosine B (ERB) under buffer conditions have been observed through experiments. After the excitation was maintained at 504 nm, the emission wavelength was measured at 556 nm. The outcome demonstrated that the amount of DXC added to the mixture causes the fluorescence of erythrosine to be correspondingly quenched. This system functions best at a pH of 3.6. The research demonstrates the potential of ERB as a complexing agent for DXC quantitative analysis through complex ion formation.
Co-Authors Aditya Singgih Raharjo Asmiyenti Djaliasrin Djalil