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Database of Herbal Medicines from Various Scientific Sources Oeke Yunita; Titin Yolanni Sun; Farah Zalfa Rofifah; Dyas Kristanto; Krisyanti Budipramana
Jurnal Pharmascience Vol 9, No 2 (2022): Jurnal Pharmascience
Publisher : Program Studi Farmasi FMIPA Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jps.v9i2.13757

Abstract

Informasi baru untuk penelitian dan pengembangan obat herbal (jamu) tidak dapat dikumpulkan dari satu database (basis data). Sumber informasi harus lengkap dan menyeluruh sehingga memungkinkan adanya referensi silang untuk memberikan informasi baru dalam penemuan dan pengembangan obat herbal. Pada review ini, kami memberikan gambaran yang komprehensif tentang sumber-sumber informasi herbal, serta deskripsi dari semua basis data yang relevan dengan obat herbal. Basis data PubMed, Science Direct, Google Scholar dan Semantic Scholar ditelusuri dalam rentang waktu antara Juni dan Juli 2021 terkait publikasi yang relevan dengan basis data jamu. Hasil perbandingan menunjukkan bahwa ETM-DB adalah basis data yang paling lengkap dan menyeluruh untuk penelitian terkait penemuan dan pengembangan obat herbal dari semua basis data yang diulas dalam penelitian ini. Ketersediaan dan kelengkapan informasi, kemampuan pengguna atau peneliti untuk melakukan penelitian dan pengembangan tambahan terhadap suatu obat herbal, serta tersedianya fitur untuk mengunduh informasi dan struktur kimia dalam berbagai versi, semuanya dapat memberikan informasi penting bagi pengembangan suatu basis data obat herbal dalam bentuk situs web penelusuran online yang mudah digunakan yang dapat diakses oleh pakar dan masyarakat umum. Pengembangan herbal dapat menggunakan basis data obat herbal, seperti yang termasuk dalam ulasan ini, untuk mengumpulkan informasi herbal yang komprehensif dari berbagai sumber. Kata Kunci: Database, Herbal, Informasi, Review  Multiple databases are utilized since new information for herbal medicine research and development cannot be obtained from a single database. Information sources must be comprehensive and complete in order to allow for cross-referencing and give new information in the discovery and development of herbal medicines. In this review, we provide a comprehensive overview of these resources, as well as descriptions of all databases that are relevant to the subject of herbal medicine. The databases PubMed, Science Direct, Google Scholar and Semantic Scholar were searched between June and July 2021 for publications relevant to herbal medicine databases. Comparison results show that ETM-DB is the most extensive database for herbal medicine drug discovery and development research of all the databases reviewed in this study. The availability and completeness of information, the ability of users or researchers to conduct additional research and development on herbal medicine, and the availability of features for downloading information and chemical structures in various versions, can all provide critical information for the development of herbal database in the form of an easy-to-use query website that is accessible. Herbal medicine development can use databases to collect comprehensive information from a variety of sources.
The Antibacterial Activities of Piper betle and Allium cepa Extracts Against Staphylococcus aureus Vendra Setiawan; Nathanel Triono; Astrid Karindra Agustina; Lovely Anastasia Moira; Verna Biutifasari; Krisyanti Budipramana
Jurnal Penelitian Pendidikan IPA Vol 11 No 9 (2025): September
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v11i9.10850

Abstract

Indonesia rich in biodiversity, both animals and plants. This is known as ethnobotany. Local people learn to use natural herbs to meet their daily needs, and some commonly used herbs are Piper betle (betel leaf) and Allium cepa (red onion). They often use P. betle or A. cepa to cure various skin infections, one of which is furuncles. This study aimed to explore ethanol extracts of P. betle, A. cepa, and their combination against Staphylococcus aureus, the main bacterial cause of furuncles, using petri dish. The inhibition zones in petri dishes were measured using a caliper to evaluate the antibacterial efficacy. Each sample was tested with 3 replicates and kanamycin was used as positive control. The P. betle extract exhibited the strongest inhibitory effect with an inhibition zone of 17.70 ± 0.30 mm, followed by P. betle and A. cepa with ratio 1:1 produced an inhibition zone of 15.63 ± 0.58 mm. The ethanol extract of A. cepa showed the lowest inhibition zone only 14.38 ± 0.35 mm and this inhibition zone was similar to that of kanamycin as positive control.