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All Journal Asean Journal of Science and Engineering (AJSE) AGROMAKNA: Jurnal Pertanian dan Peternakan
Diah Puspita Sari
Universitas Pendidikan Indonesia
Agriculture, Biological Sciences & Forestry Chemical Engineering, Chemistry & Bioengineering Computer Science & IT Engineering Materials Science & Nanotechnology

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The Effectiveness of Mugwort Leaf Extract and Gotu Kola Leaf Extract against Acne Bacterial Activity Diah Puspita Sari; Shintya Yuniar; Siti Awalia Nur Fadillah; Afifi Mutiarani; Diah Kusumawaty
ASEAN Journal of Science and Engineering Vol 2, No 3 (2022): AJSE: December 2022
Publisher : Universitas Pendidikan Indonesia (UPI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (835.089 KB) | DOI: 10.17509/ajse.v2i3.39634

Abstract

Acne is a problem among teenagers generally caused by bacterial infections such as Propionibacterium acnes, Staphylococcus aureus, and Staphylococcus epidermidis. Mugwort (Artemisia vulgaris L.) and Gotu Kola (Centella asiatica L.) extracts have antibacterial activity formulated in anti-acne gel preparations. The purpose of this study was to test and obtain a gel formula of mugwort leaf extract and gotu kola leaf extract which effectively kills and controls the growth of acne-causing bacteria. The methods used in this study include simplicity making, leaf extraction, making anti-acne gel preparations, testing pH, homogeneity, inhibition, and data analysis. The extract obtained by maceration was made in three concentrations, namely 2.50; 5.00; and 10.00%. The results showed that the pH value of the gel preparations obtained was in the range of 8.08-9.96. Mugwort leaf extract, gotu kola leaf, and mugwort-gotu kola have a distinctive smells with a thick texture at a concentration of 2.50% and a liquid texture at a concentration of 10.00%. Inhibition tests showed that the mugwort extract sample had a value of 16-18 mm, while the gotu kola extract and mugwort-gotu kola had a value of 14 mm. Mugwort leaf extract is able to inhibit the growth of acne-causing bacteria. This success was obtained because the extracts of mugwort and gotu kola leaves contain flavonoids that can inhibit the growth of bacteria that cause acne. Mugwort leaf extract gel with a concentration of 2.50 and 5.00% had the largest zone of inhibition in inhibiting P. acnes bacteria compared to other concentrations.
Potensi Bakteri Saluran Pencernaan Ikan Sidat Sebagai Antibiotik Diah Puspita Sari; Wahyuni Sultan; Abdullah Rasyad; Diah Kusumawaty
AGROMAKNA: Jurnal Pertanian dan Peternakan Vol. 1 No. 2 (2026): AGROMAKNA: Jurnal Pertanian dan Peternakan
Publisher : PT ADRIANI MANDIRI PUBLISHER

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Abstract

Anguilla bicolor bicolor is a species of eel found in Indonesian waters. This species of eel has a high economic value and the export commodity of eel has increased, especially in Japan. Bacteria in the digestive tract of eels have the potential as antibiotics which is one way of treating and preventing diseases in the fisheries sector. This study aim to identify bacteria in the digestive tract of eel that have the potential as antibiotics. The search for data on eel digestive tract bacteria that have the potential as antibiotics was carried out by reviewing literature and secondary data then analyzed descriptively and processed using Microsoft Excel and Microsoft Word. The result showed from metagenomic data, obtained 3 genera of bacteria that have the potential as antibiotics, Bacillus, Enterococcus, and Streptomyces. In the eel elver wild phase, the bacteria that had the highest abundance was the genus Bacillus. In the eel fingerling wild phase, the highest abundance of bacteria was from the genus Enterococcus.
Co-Authors Abdullah Rasyad Afifi Mutiarani Diah - Kusumawaty Shintya Yuniar Siti Awalia Nur Fadillah Wahyuni Sultan