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Krisna Dwi Purnomo Jati
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Health Professions Medicine & Pharmacology Public Health

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The VARIATION OF THE AXIAL LOCATION OF BRUCH’S MEMBRANE OPENING, GANGLION CELL INNER PLEXIFORM LAYER AND FLUX INDEX IN NORMAL TENSION GLAUCOMA AND PRIMARY OPEN ANGLE GLAUCOMA PATIENTS Jehan Fauzi Jehan; Retno Ekantini; Tatang Talka Gani; Krisna Dwi Purnomo Jati
Majalah Oftalmologi Indonesia Vol 49 No 2 (2023): Ophthalmologica Indonesiana
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/journal.v49i2.100660

Abstract

Introduction. Bruch’s membrane opening (BMO) at the most anterior point of the neural canal for quantification of cup depth /based on retinal surface position, area and volume, laminar position, and prelaminar connective tissue volume. If these deep structural parameters are to be used effectively in glaucoma detection and identification of progression. Purpose. This study explores variation in the axial location of Bruch’s membrane opening (BMO) to determine if this reference plane varies with NTG and POAG patients. Methods This was a cross-sectional prospective descriptive study with purposive sampling. This study enrolled 72 eyes in Sardjito General Hospital  underwent  cirrus – OCT 5000 Ver 11.0.0.29946  between 1st March 2022 and 10th May 2022. Results. We evaluated 72 (25 NTG and 47 POAG)  eyes on 37 outpatients service of Sardjito General Hospital. Median BMO, GCIPL, Flux index and CD ratio of NTG patients was 1.707 µm (1.387-2.182), 83,0µm (76-88), 0,40 (0.27-0,48), 0,64 (0,22-0,75). Median BMO, GCIPL, Flux index  and CD ratio of POAG patients was 1.612 (1.028-2.031) µm, 79,00 (56-98) µm, 0,40 (0,26-0,47) and 0,64 (0,28-0,92) for CDR. Bruch’s membrane opening position was more posterior relative to the sclera in older subjects with negative correlation (P value = 0,07). Variable BMO and GCIPL tested between NTG and POAG group showed significant difference with BMO P value =0,04 and GCIPL P value=0,01 except Perfusion, flux index and RNFL. Conclusion. Bruch’s membrane opening is more posteriorly located in older individuals. There was significant difference p value of BMO between the mean of NTG and POAG.
Evaluation of Cup Disc Ratio and RNFL Thickness Based on Goldmann Visual Field Test Tatang Talka Gani; Retno Ekantini; Hartono Hartono; Krisna Dwi Purnomo Jati
Majalah Oftalmologi Indonesia Vol 48 No 2 (2022): Ophthalmologica Indonesiana
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/journal.v48i2.100665

Abstract

Introduction and Objective : To assess the relationship between the cup-disc ratio of the optic nerve head and peripapilarry RNFL thickness to the visual field loss in glaucoma patients. Methods : Visual field from Goldmann kinetic perimerty and Ocular Computed Tomography (OCT) records from Yap Eye Hospital, Yogyakarta are used to examine the figure of visual field loss in glaucoma patient. Result: Broad spectrum of glaucoma-related visual field defects were observed from 73 eyes. The most common visual field defects are arcuate defect (23.3%) and followed by general depression. Arcuate defects can already observable in some patients with cup-disk ratio of 0.5 (30%).Arcuate defect occurs in the average RNFL thickness of 69.90 ?m (46.93-118.77). It appears that the pinhole vision appeared on the average RNFL thickness of 44.23 ?m (25.33-63.13), and temporal RNFL thickness remnant occured at 48.64 ?m (46.22-51.06). RNFL thickness with normal visual field was on the thickness of 107.78 ?m (100.27-115.29). Conclusion: Visual field defect that may be observed in glaucoma with Goldmann kinetic perimetry are arcuate defect, and general visual field depression. RNFL thickness may be correlated longitudinally with the worsening of visual field defect.
PERBANDINGAN SIKLOKRIOTERAPI KOMBINASI DENGAN RETROBULBAR KLORPROMAZIN VS SIKLOKRIOTERAPI SAJA DALAM MENURUNKAN TEKANAN INTRAOKULAR DAN NYERI PADA GLAUKOMA TAHAP AKHIR Muhammad Raditya Fadhil Fadhil; Retno Ekantini; Tatang Talka Gani; Krisna Dwi Purnomo Jati
Majalah Oftalmologi Indonesia Vol 49 No 2 (2023): Ophthalmologica Indonesiana
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/journal.v49i2.100690

Abstract

Introduction: Patients with end-stage glaucoma often came with a painful blind eye. One of the managements is cyclocryotherapy (CCT) or retrobulbar chlorpromazine (CPZ). In this study, we aimed to evaluate the combined use of cyclocryotherapy and retrobulbar chlorpromazine versus cyclocryotherapy alone in reducing the intraocular pressure (IOP) and Visual Analog Scale (VAS) pain scores in end-stage glaucoma patients. Methods: Samples were taken from patients who enrolled in the Ophthalmology Clinic of Dr. Sardjito General Hospital from October 2021 to March 2022. Samples were then divided into 2 groups, the CCT+CPZ group received the combination of cyclocryotherapy and retrobulbar chlorpromazine and the CCT group received only cyclocryotherapy. IOP and VAS pain scores pre-operation and 30th-day post-operation were examined.  Results: Thirty-three patients were included in the CCT+CPZ group and 17 patients were included in the CCT group. The mean IOP and VAS pain scores 30th-day post-operation in the CCT+CPZ group were 22.6±10.3 mmHg and 1.6±1.3 vs pre-operation 44.9±19.5 mmHg and 7.9±1.7 (p=0.000). Patients in the CCT group also show a significant reduction in both mean IOP and VAS pain scores 31.4±16 mmHg and 2.6±2.3 vs pre-operation 54.4±7.4 mmHg and 8.4±2.1 (p=0.001). Both IOP and VAS pain scores at 30th-day post-operation were significantly lower in the CCT+CPZ group compared to the CCT group (p=0.030 and p=0.013, respectively). Conclusion: There were statistically significant differences between patients who received a combination of cyclocryotherapy and retrobulbar chlorpromazine in reducing the IOP and VAS pain score compared with patients who received only cyclocryotherapy.
Co-Authors Hartono Hartono Jehan Fauzi Jehan Muhammad Raditya Fadhil Fadhil Retno Ekantini Tatang Talka Gani