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All Journal JIFI (Jurnal Ilmiah Farmasi Imelda) Jurnal Sains dan Teknologi Celebes Journal of Community Services
Dina Maya Syari
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Aerospace Engineering Agriculture, Biological Sciences & Forestry Humanities Automotive Engineering Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Control & Systems Engineering Dentistry Economics, Econometrics & Finance Education Electrical & Electronics Engineering Energy Engineering Health Professions Industrial & Manufacturing Engineering Mathematics Mechanical Engineering Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary

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UJI AKTIVITAS ANTI BAKTERI EKSTRAK ETANOL 96% DAUN TEH-TEHAN (Acalypha siamensis) PADA BAKTERI Escherichia coli DENGAN MENGGUNAKAN METODE CAKRAM Dina Maya Syari; Patriza, Zahra Sukma
JIFI (Jurnal Ilmiah Farmasi Imelda) Vol. 6 No. 1 (2022): JIFI (Jurnal Ilmiah Farmasi Imelda)
Publisher : Universitas Imelda Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52943/jifarmasi.v6i1.1120

Abstract

Teh-tehan (Acalypha siamensis) is a plant that has many branches including a bush with a height of 1-2 m. Escherichia coli bacteria can be found in the human intestine, most of these bacteria are harmless, but some can cause serious poisoning in humans such as diarrhea. The purpose of this study was to determine the antibacterial activity of the ethanol extract of tea-tea leaves (Acalypha siamensis) against Escherichia coli bacteria using the disc method. This research is descriptive by using the ratio of the extract concentration of 20%, 30%, 50%, and 80% with a positive control of chloramphenicol and a negative control of aquadest. he results showed that the concentration of ethanol extract had antibacterial activity. Escherichia coli bacteria gave the highest inhibition zone at a concentration of 80% with an inhibition zone diameter of 12.8 mm while the control chloramphenicol was 28.5 mm. Based on the ANOVA data analysis test that there is a significant difference in antibacterial inhibition.
Sosialisasi dan Pelatihan Penggunaan Obat yang Rasional bagi Masyarakat Pedesaan Auliafendri, Novycha Auliafendri; Dina Maya Syari; Roby Pahala Januario Gultom; Sri Rezeki Samosir; Mutiara Siahaan
Celebes Journal of Community Services Vol. 3 No. 2 (2024): Juni - November
Publisher : STIE Amkop Makassar, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37531/celeb.v3i2.1634

Abstract

Penggunaan obat yang rasional adalah kunci untuk meningkatkan kesehatan masyarakat, terutama di daerah pedesaan yang sering menghadapi tantangan dalam akses informasi kesehatan. Program pengabdian masyarakat di Dusun Ulu, Kecamatan Ujung Padang, Sumatera Utara, bertujuan untuk meningkatkan pemahaman masyarakat tentang penggunaan obat yang benar melalui presentasi, pelatihan pengenalan obat, dan diskusi kelompok. Sasaran kegiatan ini adalah penduduk berusia 21-45 tahun yang merupakan pengelola utama kesehatan keluarga. Hasil pretest dan posttest menunjukkan peningkatan signifikan dalam pemahaman masyarakat mengenai penggunaan obat yang rasional. Partisipasi aktif masyarakat dan kolaborasi dengan tenaga kesehatan lokal memainkan peran penting dalam keberhasilan program ini. Diskusi kelompok memberikan platform bagi masyarakat untuk berbagi pengalaman dan belajar secara interaktif, sementara tenaga kesehatan lokal berkomitmen untuk melanjutkan edukasi setelah program berakhir. Program ini tidak hanya berhasil meningkatkan pengetahuan masyarakat tetapi juga membangun jaringan informasi kesehatan yang dapat digunakan untuk meningkatkan kesehatan komunitas secara berkelanjutan. Kesimpulannya, program ini membuktikan efektivitas pendekatan berbasis edukasi dan kolaborasi dalam meningkatkan praktik penggunaan obat yang rasional di masyarakat pedesaan.
Analisis Potensi Hasil Fraksinasi Dari Ekstrak Etanol Daun Pacing (Costus spicatus (Jacq.) Sw.) sebagai Bahan Baku Obat Herbal terhadap Uji Aktivitas Pertumbuhan Rambut Kelinci Sri Rezeki Samosir; Dina Maya Syari
INSOLOGI: Jurnal Sains dan Teknologi Vol. 4 No. 5 (2025): Oktober 2025
Publisher : Yayasan Literasi Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55123/insologi.v4i5.6582

Abstract

Hair growth disorders can be caused by many factors, one of which is oxidative stress and immunity, which can lead to baldness (alopecia). This study aims to analyze the potential of pacing leaf fractionation on rabbit hair growth. This research method is experimental in nature and conducted in a laboratory. The extraction stage uses the maceration method with 96% ethanol solvent for 3 days. The fractionation stage uses n-hexane and ethyl acetate solvents using a separating funnel. Based on the evaporation results, n-hexane fraction (FHE), ethyl acetate fraction (FEA), and ethanol fraction (FET) were obtained. Phytochemical tests for each fraction showed that FEA and FET contained flavonoids, alkaloids, tannins, saponins, and steroids/terpenoids. However, FHE only contained alkaloids and steroids. A total of 5 male rabbits were adapted and marked with 5 areas on their backs to be applied with FHE, FEA, and FET at a concentration of 50%, minoxidil 2% as K(+), and Na-CMC as K(-). Hair growth was observed for 28 days. The results showed that the activity of FET and FHE on day 28 resulted in good hair length, with an average hair growth of 2.22±0.101 mm and 2.15±0.064 mm for both fractions, and an average hair weight of 0.19±0.024 g and 0.19±0.015 g. Each fraction affected rabbit hair growth (p<0.05), The growth rate, FHE, FET, and K(+) did not differ significantly in terms of hair weight (p>0.05). However, the growth and hair weight results from minoxidil administration were still better than the overall fraction.
Co-Authors Auliafendri, Novycha Auliafendri Mutiara Siahaan Patriza, Zahra Sukma Roby Pahala Januario Gultom Sri Rezeki Samosir