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Ari Astram
Universitas Sam Ratulangi
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Nursing Public Health

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Journal : e-CliniC

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Bacterial Profile and Antibiotic Susceptibility Pattern of Patients at Pre- and Post-Urologic Endoscopy Procedures at Prof. Dr. R. D. Kandou Hospital, Manado, Indonesia Paulus Oroh; Ari Astram; Christof Toreh; Eko Arianto; Frendy Wihono; Windy Wariki; Hessyani Raranta
e-CliniC Vol. 11 No. 1 (2023): e-CliniC
Publisher : Universitas Sam Ratulangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35790/ecl.v11i1.44315

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Abstract: Development of antibiotics resistance condition has been at a concerning state while data on the distribution of bacterial profile and the incidence of resistances in Indonesia are currently still limited at hospital environment, including at Prof. Dr. R. D. Kandou Hospital in Manado, Indonesia. This study aimed to obtain the profile of bacteria and the pattern of susceptibility to antibiotics in patient's urine before and after urologic endoscopy procedures at RSUP Prof. Dr. R. D. Kandou. This was an observational study with a cross sectional design. Sampling was performed with the one-group test technique of Lemeshow. The data collection technique used urine culture test by calculating the percentages. The results obtained 42 patients as subjects. The urinary bacterial profile of patients who underwent urologic endoscopy procedures at Prof. Dr. R. D. Kandou Hospital were dominated by Gram-negative bacteria, namely E. coli (23.8%), Klebsiella (4.8%), Acinetobacter baumannii (2.4%); 69% of urine samples showed negative culture results. The susceptibility pattern of bacteria to antibiotics in the subjects’ urine showed 100% sensitivity to the given antibiotics. No nosocomial infection was found, however, nosocomial infection yet could not be excluded. In conclusion, bacteria found in the patients’ urine are dominated by Gram-negative bacteria namely Escherichia coli, Klebsiella, and Acinetobacter baumannii which are still sensitive to antibiotics. Most urine samples showed negative results, and no nosocomial infection was found. Keywords: bacterial profile; bacterial susceptibility; antibiotic; urological endoscopic procedure
Karakteristik Pasien Operasi Rekonstruksi Hipospadia yang Menjalani Terapi Oksigen Hiperbarik di RSUP Prof. Dr. R. D. Kandou dan RS Siloam Manado Irawan Sukarno; Ari Astram; Mendy J. Hatibie; Fredrik G. Langi
e-CliniC Vol. 12 No. 1 (2024): e-CliniC
Publisher : Universitas Sam Ratulangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35790/ecl.v12i1.46457

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Abstract: Hypospadias is a congenital abnormality of urethral meatus in male. Hypospadias can be corrected by urethroplasty. Hyperbaric oxygen therapy (HBOT) can accelerate wound healing after surgery by increasing oxygenation, angiogenesis, and collagen synthesis. This study aimed to describe the characteristics of hypospadias reconstructive surgery patients who underwent hyperbaric oxygen therapy. This was a quantitative and descriptive study. Data were analyzed with SPSS ver 22.0. The results showed that from 20 patients who underwent reconstructive hypospadias surgery, 10 patients received HBOT as adjuvant therapy and 10 patients received conservative therapy post-surgery. The mean age of patients who underwent HBOT was 17.4±7.1 years old. The most frequent type of hypospadias found was subcoronal (35%), followed by the other types: glandular (20%), distal penile (10%), midshaft penile (10%), proximal penile (10%), penoscrotal (10%), and the least was scrotal (5%). All of the patients underwent urethroplasty with Sidik-Chaula and Manset Flap method. In conclusion, the mean age of patients who underwent HBOT was 17.4±7.1 years old, and the most frequent type of hypospadias found was subcoronal. Keywords: hypospadias; hyperbaric oxygen therapy; characteristics of hypospadias patients   Abstrak: Hipospadia merupakan kelainan kongenital meatus uretra pada laki-laki. Hipospadia dapat dikoreksi dengan uretroplasti. Terapi oksigen hiperbarik (TOHB) dapat mempercepat penyembuhan luka pascaoperasi melalui peningkatan oksigenasi, angiogenesis, dan sintesis kolagen. Penelitian ini bertujuan untuk mengetahui karakteristik pasien rekonstruksi hipospadia yang menjalani TOHB. Jenis penelitian ialah deskriptif kuantitatif dengan alat analisis SPSS ver. 22.0. Hasil penelitian mendapatkan 20 pasien yang dilakukan operasi rekonstruksi hipospadia; 10 pasien menjalani TOHB dan 10 pasien menjalani terapi konservatif pasca pembedahan. Rerata usia pasien yang menjalani TOHB yaitu 17,4±7,1 tahun. Tipe hipospadia yang paling sering ialah subcoronal (35%), diikuti tipe glandular (20%), dan sisanya ialah tipe distal penile (10%), midshaft penile (10%), proximal penile (10%), penoscrotal (10%), dan yang paling sedikit ialah tipe scrotal (5%). Semua pasien menjalani operasi dengan metode Sidik-Chaula dan Manset Flap. Simpulan penelitian ini ialah rerata usia pasien yang menjalani TOHB ialah 17,4±7,1 tahun dengan tipe hipospadia yang paling sering ialah subcoronal. Kata kunci: hipospadia; terapi oksigen hiperbarik; karakteristik pasien hipospadia
Co-Authors Christof Toreh Eko Arianto Fredrik G. Langi Frendy Wihono Hessyani Raranta Irawan Sukarno Mahesa Krishna Marcella Merung Mendy Hatibie Paulus Oroh Ronald J. Datu Wariki, Windy M. V.