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All Journal Asian Journal of Health Research
Lita Setyowatie
Department of Dermatology and Venerology, Faculty of Medicine, Universitas Brawijaya/Saiful Anwar General Hospital, Malang East Java, 65145, Indonesia
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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Case Report: Combination of Electrocautery and Echinacea Therapy in Condylomata Acuminata Raras Pratita; Lita Setyowatie
Asian Journal of Health Research Vol. 1 No. 3 (2022): Volume 1 No 3 (December) 2022
Publisher : Ikatan Dokter Indonesia Wilayah Jawa Timur

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55561/ajhr.v1i3.48

Abstract

Introduction: Condylomata acuminata or genital warts are classified as sexually transmitted infections caused by the Human Papilloma Virus. The main purpose of Condylomata acuminata treatment is to remove warts and prevent recurrence. Monotherapy is often unsatisfactory. Combination therapy can be done for a better response and minimizing recurrences, one of which is by using an immunomodulator, namely Echinacea. Case Presentation: A 47-years-old woman, widowed, heterosexual, with complaints of genital warts since 2 months ago. Dermatovenerological examination on the major and minor labia showed papules with skin and mucosa color, verucose, multiple, no tenderness and no bleeding. Inspeculo examination found no lesions on the vaginal wall. The acetowhite test showed a positive white color. Patient was diagnosed with condylomata acuminata. The patient received electrocauter therapy once and Echinacea 500 mg for 3 months. Follow-up for 6 months did not reveal any new or recurrent lesions. Conclusion: Therapy for condylomata acuminata is still challenging. Monotherapy is often unsatisfactory due to high degree of recurrence. The use of combination therapy is aimed at minimizing recurrences, one of which is the use of imunomudulator. In this case report, there were no relapses in the 6th month of follow up with combination treatment. These case report can increase knowledge about therapeutic options for CA to avoid recurrences.
Case Report: Secondary Syphilis And Human Immunodeficiency Virus Coinfection Lita Setyowatie; Adya Sitaresmi
Asian Journal of Health Research Vol. 1 No. 3 (2022): Volume 1 No 3 (December) 2022
Publisher : Ikatan Dokter Indonesia Wilayah Jawa Timur

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55561/ajhr.v1i3.50

Abstract

Introduction: Syphilis is a sexually transmitted infection that is chronically progressive, with a broad spectrum of active clinical and asymptomatic periods. A total of 80.6% of men with syphilis were Men Who Sex with Men (MSM), 47% of the population was coinfected with Human Immunodeficiency Virus (HIV). Case Presentation: Male, 23-yo, MSM, unmarried, HIV, complaining of red bumps and spots on the palms, soles, and upper arms since 4 days ago. One week earlier, he complained of sores in the genitals, which recurred 1 year ago and healed on their own. Dermatological examination revealed multiple erythematous patches and papules. The corpus penis, glans penis, and scrotum showed erosions and multiple ulcers with an erythematous-based, covered with yellowish crusts. VDRL and TPHA were reactive. The patient was diagnosed with secondary syphilis and treated with an intramuscular injection of benzathine penicillin 2.4 million IU once. A 1-month evaluation showed significant lesion improvement, VDRL titer 1:64. Evaluation of the 3rd and 6th months revealed a VDRL titer of 1:4. Conclusion: The clinical manifestations of syphilis patients with HIV coinfection are generally more atypical, aggressive, and overlap caused by changes in the immune system in HIV infection. Unsafe sexual behavior in MSM increases the transmission of syphilis infection. Diagnosis and therapy are generally the same. Men Who Sex with Men is a factor that allows the transmission of syphilis in HIV patients. Administration of benzathine penicillin injection once gave lesion improvement and significantly reduced VDRL.
Co-Authors Adya Sitaresmi Raras Pratita