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A. Sri Rahmadani
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Education Immunology & microbiology Medicine & Pharmacology Public Health Veterinary

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Pemanfaatan Tepung Cangkang dan Kepala Udang Vaname (Litopenaeus vannamei) terhadap Penurunan Hiperkolesterolemia secara In Vivo Rosdiana Ngitung; Sahribulan Sahribulan; A. Sri Rahmadani
bionature Vol 23, No 2 (2022): Oktober
Publisher : Fakultas MIPA UNM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35580/bionature.v23i2.37712

Abstract

Penelitian ini bertujuan untuk mengetahui pengaruh dan konsentrasi optimum pemberian tepung cangkang dan kepala udang vaname (Litopenaeus vannamei) terhadap penurunan hiperkolesterolemia pada mencit (Mus musculus). Penelitian ini terdiri dari 4 kelompok perlakuan yaitu P0 (pakan hiperkolesterol dicampur tepung cangkang dan kepala udang sebesar 0%), P1 (pakan hiperkolesterol dicampur tepung cangkang dan kepala udang sebesar 5%), P2 (pakan hiperkolesterol dicampur tepung cangkang dan kepala udang sebesar 7%), dan P3 (pakan hiperkolesterol dicampur tepung cangkang dan kepala udang sebesar 9%). Metode penelitian terdiri dari beberapa tahap yaitu pembuatan pakan hiperkolesterol, pembuatan tepung cangkang dan kepala udang, pembuatan pakan perlakuan hewan uji, perlakuan hewan uji, serta pengukuran kadar kolesterol. Analisis data menggunakan uji One Way ANOVA dan uji lanjut Duncan. Hasil penelitian menunjukkan nilai rata-rata kadar kolesterol awal kelompok perlakuan P3 berbeda sangat nyata terhadap kelompok perlakuan P0, P1, dan P2. Nilai rata-rata kadar kolesterol akhir kelompok perlakuan P2 berbeda sangat nyata terhadap P0 dan berbeda nyata terhadap P1 dan P3. Hasil penelitian menunjukkan bahwa konsentrasi tepung cangkang dan kepala udang paling optimum ialah 7% (P2) yang mampu menurunkan hiperkolesterolemia pada mencit (Mus musculus) sebesar 0.29%.
Pemanfaatan Tepung Cangkang dan Kepala Udang Vaname (Litopenaeus vannamei) terhadap Penurunan Hiperkolesterolemia secara In Vivo Rosdiana Ngitung; Sahribulan; A. Sri Rahmadani
Bionature Vol. 23 No. 2 (2022): Oktober 2022
Publisher : Jurusan Biologi Universitas Negeri Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

This research is an experimental study that aims to determine the effect and optimum concentration of shelland head of white shrimp (Litopenaeus vannamei) on reducing hypercholesterolemia in mice (Mus musculus).This study consisted of 4 treatment groups: P0 (hypercholesterol feed mixed with 0% shrimp shell and head flour),P1 (hypercholesterol feed mixed with 5% shrimp shell and head flour), P2 (hypercholesterol feed mixed with 7%shell and shrimp head flour), and P3 (hypercholesterol feed mixed with 9% shell and shrimp head flour). Theresearch method consisted of the manufacture of hypercholesterolemic feed, the manufacture of shell and shrimphead flour, the manufacture of test animal feed, treatment of test animals, and measurement of cholesterol levels.Data were analyzed using One Way ANOVA and Duncan's test. The average value of initial cholesterol levels inthe P3 treatment group was very significantly different from the P0, P1, and P2 treatment groups. The mean valueof final cholesterol levels in the P2 treatment group was significantly different from P0 and significantly differentfrom P1 and P3. The optimum concentration was 7% (P2) which was able to reduce hypercholesterolemia in mice(Mus musculus) by 0.29%.
Co-Authors Rosdiana Ngitung Sahribulan Sahribulan Sahribulan