<![CDATA[Objective: This case report discussed the clinical picture of SLE patients with oral manifestations related to thrombocytopenia. Two-Case Reports: The first patient was consulted from the Pediatric department, a 13-year-old-girl complaint oral canker sores about 2 weeks before hospitalization, accompanied by fever and difficulty in eating. The second patient was an 18-year-old-woman consulted from the Internal Medicine department with complaints of bleeding gums and lips before hospitalization. Blood tests in both patients showed a decrease in value of hemoglobin, hematocrit, erythrocytes, leukocytes and thrombocytes. Results: Systemic Lupus Erythematosus was diagnosed with Anti-ds DNA examination for the first patients, while the second one did with ANA test. Management of oral lesions for the first patient, given a solution of dexamethasone by sterile gauge to compress lips, gargling with 0.2% chlorhexidine gluconate, vitamin B12, folic acid, and petroleum jelly for her lips. The second patient gave an 1% ferracrylum mouthwash, 0.9% NaCl compresses on the lips, 0.1% chlorhexidine gluconate and a smear thin layer of petroleum jelly on her lips. The condition of the two patients improved after two weeks so that they could gradually consume solid food and be allowed to go home. Conclusion: In-depth history, complete examination, comprehensive multidisciplinary approach related to manifestations of SLE has a significant effect in reducing the severity of the disease due to oral lesions and improving quality of patients life.]]>
