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All Journal Ahmad Dahlan Medical Journal
Elvina Prisila
Ahmad Dahlan University
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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Chronic Osteomyelitis After a Partial Internal Fixation Surgery: A Case Report Elvina Prisila; Moch. Junaedy Heriyanto
Ahmad Dahlan Medical Journal Vol. 3 No. 2 (2022): November 2022
Publisher : Universitas Ahmad Dahlan

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Abstract

Chronic osteomyelitis is a condition of acute osteomyelitis that has failed to heal because appears as long-lasting and refractory disease in which bacteria may produce biofilms consisting of matrix proteins and polysaccharides to protect the bacteria from antibiotics and monocyte-macrophage system obliteration.1,2 We report a 40-years-old man with a history of postoperative open fracture of the right femur 6 months ago. Pain (+). X-ray examination showed the results: attached plate and screw with nonunion old fracture of the femoral dextra alignment and less apposition with sclerotic features, osteodestruction of the left femoral system, leading to osteomyelitis. Then performed a partial internal fixation removal operation. From the results obtained from the patient, it was concluded that there was osteomyelitis in the femur due to complications from a postoperative open fracture of the right femur.
Gaucher’s Disease : A Case Report Elvina Prisila; Ana Majdawati
Ahmad Dahlan Medical Journal Vol. 4 No. 1 (2023): May 2023
Publisher : Universitas Ahmad Dahlan

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Gaucher disease is a rare genetic disorder in which a person lacks an enzyme called glucocerebrosidase (GBA). Gaucher disease is an autosomal recessive inherited disorder of metabolism where a type of fat (lipid) called glucocerebroside cannot be adequately degraded. The lack of the GBA causes harmful substances to build up in the lung, liver, spleen, bones, and bone marrow, brain and eyes. These substances prevent cells and organs from working properly. There are three recognized Types of Gaucher disease and each has a wide range of symptoms. Type 1 is the most common, does not affect the nervous system and may appear early in life or adulthood. Many people with Type 1 Gaucher disease have findings that are so mild that they never have any problems from the disorder. Type 2 and 3 do affect the nervous system. A man, 27th, goes to the hospital with pain at upper of left knee, swollen since 3 week ago, hypertension(-), DM (-), history of left knee operation. Traumatic history (-). HB: 14,9mmgr/dl, AL 7,6. AT 186, HMT 43,8%, GDS 95 mg/dl, APTT 34,4. PPT: 11,6, diff eosinophil: 3,2. From the symptoms dan clinical finding from this patient we can make conclusion, the case is typical Gaucher disease type 1.
Co-Authors Ana Majdawati Moch. Junaedy Heriyanto