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Challenges and Opportunities in Implementing Tuberculosis Prevention Therapy in Developing Countries: A Scoping Review Brigadini Ayuning Putri; Martha Irene Kartasurya; Bagoes Widjanarko
Eduvest - Journal of Universal Studies Vol. 5 No. 11 (2025): Eduvest - Journal of Universal Studies
Publisher : Green Publisher Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59188/eduvest.v5i11.52435

Abstract

Tuberculosis Prevention Therapy (TPT) is an effort to prevent tuberculosis (TB) in people who have close contact with TB-positive patients. However, the challenges and opportunities in implementing TPT have not been fully explored. This study aims to examine the challenges and opportunities in implementing TPT within health services in developing countries. A systematic search was conducted using electronic databases (Scopus, PubMed, Science Direct, ProQuest) for literature published between 2015 and 2025. Following the PRISMA-ScR guidelines, 10 articles from various developing countries were included in the final analysis. Studies available in English with quantitative or qualitative designs and free full-text access were selected. The findings reveal that limited access to health services, inadequate health resources, insufficient knowledge, and adverse social environments constitute the primary challenges to implementation. Conversely, stakeholder support and strategic development of health services present significant opportunities to improve TPT uptake and completion. These insights provide evidence-based guidance for policymakers and healthcare practitioners to formulate targeted strategies that address implementation barriers and leverage existing opportunities to reduce the TB burden in resource-limited settings.
Causes and risk factors of neonatal mortality through the AMP-SR framework: a scoping review in Indonesia Sulicha Nurhayati; Martha Irene Kartasurya; Cahya Tri Purnami
International Journal of Public Health Science (IJPHS) Vol 15, No 1: March 2026
Publisher : Intelektual Pustaka Media Utama

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11591/ijphs.v15i1.26918

Abstract

Neonatal mortality in Indonesia continues to increase, especially during the first 0-6 days of life, indicating persistent gaps in the quality of maternal and neonatal care. The maternal perinatal surveillance and response audit (AMP-SR) is implemented to identify causes of death and guide preventive and curative actions. This scoping review aims to explore the causes and risk factors of neonatal mortality using the AMP-SR framework. Article searches were conducted in Google Scholar, Garuda, and PubMed using the keywords (“Neonatal Death” OR “Cause of Death” OR “Kematian Neonatal”) AND (“AMP-SR” OR “Death Notification”). Inclusion criteria comprised primary studies published in Indonesian or English between 2021 and 2025 that examined neonatal deaths using the AMP-SR approach. Seventeen articles were selected and thematically analyzed following the PRISMA guidelines. The main causes of neonatal death were clinical conditions, including asphyxia, prematurity, sepsis, hypothermia, and congenital abnormalities. Identified risk factors encompassed maternal age, pregnancy complications, referral delays, inadequate quality of care, and limited health worker competence. Most neonatal deaths occurred within the first 72 hours of life, predominantly among male infants with low birth weight or gestational age under 37 weeks. These findings demonstrate that neonatal mortality results from interconnected medical, maternal, and health system factors that can be systematically identified through AMP-SR. From a policy and practice perspective, strengthening the routine use of AMP-SR findings to inform targeted quality improvement, referral system strengthening, and workforce capacity-building is essential to reduce preventable neonatal deaths in Indonesia.