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All Journal Majalah Kedokteran Bandung Bandung Conference Series : Medical Science
Sara Puspita
Fakultas Kedokteran, Universitas Islam Bandung
Humanities Medicine & Pharmacology Nursing Public Health

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Positive Lateral Flow Urine Lipoarabinomannan Assay (LF-LAM) Result in Detection of Active Tuberculosis Sara Puspita; Dewi Kartika Turbawaty; Nina Tristina; Leni Lismayanti
Majalah Kedokteran Bandung Vol 53, No 3 (2021)
Publisher : Faculty of Medicine, Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15395/mkb.v53n3.2265

Abstract

Lipoarabinomannan (LAM) is the main component of M. tuberculosis (MTB) wall as result of MTB degradation by macrophages in the human body. In patients with active TB and HIV co-infection, a decrease in antibody responses may be apparent that some of LAM may not be bound with antibodies. In this condition, LAM can pass through the normal glomerular basement membrane and can be detected in the urine. One laboratory examination for detecting LAM is the Lateral Flow Urine Lipoarabinomannan (LF-LAM) assay that uses urine as the sample. The purpose of this cross-sectional observational descriptive comparative study was to compare the positivity rate of LF-LAM examination results in active TB patients with and without HIV infection. Random urine samples were collected from patients diagnosed with active TB with and without HIV infection who visited Dr. Hasan Sadikin General Hospital Bandung from August to October 2020. The proportion between the group with HIV and group without HIV was analyzed with the Chi-Square test. Subjects were 52 patients, consisting of 25 (48%) subjects with HIV infection and 27 (52%) subjects without HIV infection. The positive LF-LAM results were found in 11 (21%) subjects, consisting of 9 (36%) subjects with HIV infection and 2 (7%) subjects without HIV infection, with p=0.012. In conclusion, the positivity rate of LF-LAM results is higher in active TB patients with HIV infection compared to those without HIV infection. 
Puasa Senin-Kamis dengan Fungsi Kognisi Lanjut Usia Rumaisha Ummu Syuhada; M. Nurhalim Shahib; Sara Puspita
Bandung Conference Series: Medical Science Vol. 3 No. 1 (2023): Bandung Conference Series: Medical Science
Publisher : UNISBA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/bcsms.v3i1.5789

Abstract

Abstract. Cognition is defined as a thought process in the brain, using sensory input to the brain plus information that has been stored as memory. Cognitive function is influenced by one of them by fasting. This study aims to analyze the relationship between the intensity of Monday-Thursday fasting and cognitive function in the elderly at the Bandung City Nursing Home. This type of research is a quantitative research with analytical methods accompanied by a cross sectional approach. Sampling using probability sampling technique with total sampling method obtained 30 respondents. The method of data collection was carried out using the MMSE questionnaire instrument and interviews about fasting which were analyzed by the chi square test with the results of bivariate analysis showing a relationship between the intensity of fasting on Mondays and Thursdays with cognitive function in the elderly at the Nursing Home in Bandung City (p=0.002). The conclusion in this study is that there is an influence between intermittent fasting and cognitive function in the elderly at the Nursing Home, Bandung City. Abstrak. Kognisi diartikan sebagai proses berpikir pada otak, dengan menggunakan input sensorik yang menuju otak ditambah informasi yang telah disimpan sebagai memori. Fungsi kognisi dipengaruhi salah satunya oleh puasa. Penelitian ini bertujuan untuk menganalisis hubungan antara intensitas puasa Senin Kamis dengan fungsi kognisi pada lanjut usia di Panti Werdha Kota Bandung. Jenis penelitian ini adalah penelitian kuantitatif dengan metode analitik yang disertai dengan pendekatan cross sectional. Pengambilan sampel menggunakan tehnik probability sampling dengan metode total samplingdidapatkan 30 responden. Cara pengumpulan data dilakukan menggunakan instrumen kuesioner MMSE dan wawancara mengensi puasa yang di analisis dengan uji chi square dengan hasil analisis bivariat menunjukkan adanya hubungan antara intensitas puasa Senin Kamis dengan fungsi kognisi pada lanjut usia di Panti Werdha Kota Bandung (p=0,002). Kesimpulan dalam penelitian ini adalah terdapat hubungan antara puasa Senin Kamis dengan fungsi kognisi pada lanjut usia di Panti Werdha Kota Bandung.
Co-Authors Dewi Kartika Turbawaty Leni Lismayanti M. Nurhalim Shahib Nina Tristina Rumaisha Ummu Syuhada