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Hypertensive Crisis Siti Jaisy Millah Hadaina; Romi Ermawan; Andi Annisa Amaliah Darman; Nimas Resti; Putu Diva Gayatri Jaya Putri; Yusuf Alfin Firmawan
Jurnal Ilmiah STIKES Yarsi Mataram Vol. 13 No. 1 (2023): Jurnal Ilmiah STIKES Yarsi Mataram
Publisher : Sekolah Tinggi Ilmu Kesehatan YARSI Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57267/jisym.v13i1.224

Abstract

Hypertension in global burden disease and is expected to increase by 29% in 2025. one of the emergency condition that can arise from hypertension is hypertensive crisis. Hypertensive crisis is an increase of systolic blood pressure >179 mmHg and diastolic blood pressure > 109 mmHg. By the present of target organ damage, hypertensive crisis is classified as hypertensive urgency and hypertensive emergency.Hypertensive crisis occurs based on several mechanisms, failure of the autoregulation system, activation of renin-angiotensin-aldosterone system, and prothrombotic state. This mechanisms cause ischemia and induces a hypertensive crisis. Management of hypertensive crisis is to restore systolic blood pressure in range 100-110 mmHg. In hypertensive emergency case, blood pressure should be reduced slowly to 20-25% in first hour and 160/100 mmHg in the next 2 to 6 hours, except in hypertensive emergency case that cause aortic dissection. Therapy of hypertensive crisis including arterial and venous vasodilators, ACE inhibitor, calcium antagonists, and diuretics.
HEMOFILIA: SUATU KELAINAN PADA FAKTOR PEMBEKUAN DARAH Andi Annisa Amaliah Darman; Raehanul Bahraen
Jurnal Medika Hutama Vol. 4 No. 02 Januari (2023): Jurnal Medika Hutama
Publisher : Yayasan Pendidikan Medika Indonesia

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Abstract

Hemophilia is a disease caused by a genetic blood clotting disorder. This blood clotting disorder is X-linked hereditary due to a deficiency of clotting factors VIII or IX. Two forms are known, namely hemophilia A and hemophilia B. Hemophilia A is caused by a deficiency of factor VIII, while hemophilia B is caused by a deficiency of factor IX. The prevalence of hemophilia in the world is recorded at 400,000 cases or 1 in 10,000 live births. The diagnosis of this disease can be made on the basis of anamnesis, physical examination and supporting examinations. Hemophilia is a chronic disease that is irreversible so it has a poor prognosis. Nonetheless, the quality of life of hemophilia patients can be improved with early diagnosis and appropriate management.