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All Journal ARTERI : Jurnal Ilmu Kesehatan
Arinda Lironika
Politeknik Negeri Jember
Electrical & Electronics Engineering Health Professions Medicine & Pharmacology Nursing Public Health

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Efek Tepung Ubi Jalar Ungu Terhdap Kadar LowDensity Lipoprotein (LDL) Tikus Putih Jantan Galur Wistar Model Obesitas Vindi Atikatus Zuhro; Arisanty Nursetia Restuti; Adhiningsih Yulianti; Arinda Lironika
ARTERI : Jurnal Ilmu Kesehatan Vol 4 No 1 (2022): November
Publisher : Puslitbang Sinergis Asa Professional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37148/arteri.v4i1.258

Abstract

Obesity is a nutritional problem caused by the accumulation of excess fat than needed. The purpose of this study was to determine the effect of purple sweet potato flour on HDL levels in obese male rats. This research is a True Experimental with pre-posttest control group. Samples were 24 male wistar rats weighing 200-300 grams. Samples were taken randomly in groups (K-), rats were fed with rat bio and water ad libitum. Group (K+), rats were induced with high fat diet ad libitum and given66% fructose drink ad libitum. (P) rats were induced by ad libitum high-fat diet and given ad libitum drinking of 66% fructose and 4.5 g of purple sweet potato flour intervention. Examination of HDL levels using the CHOD-PAP method. The results of One Way Anova Test Analysis (p>0.05)before treatment between groups there was no significant difference in LDL levels. And then after treatment there was no significant difference in LDL levels between groups. However, there was a decrease in LDL levels between treatement by 4 mg/dl. It can be concluded that purple sweet potato flour did not significantly reduce LDL levels in obese rats.
Complementary Feeding Innovation from Soybean and Dragon Fruit Peel Enhances Macro- and Micronutrient Biomarkers in Malnourished Rats Rauf Muhammad Abdul; Arinda Lironika; Zora Olivi; Agatha Widiyawati
ARTERI : Jurnal Ilmu Kesehatan Vol 7 No 3 (2026): Mei
Publisher : Puslitbang Sinergis Asa Professional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37148/arteri.v7i3.784

Abstract

Malnutrition remains a major public health concern characterized by deficiencies in both macronutrients and micronutrients. The use of locally based functional foods such as soybean (Glycine max) and dragon fruit peel (Hylocereus polyrhizus) offers potential as an alternative nutritional intervention. This study aimed to evaluate the effect of soybean and dragon fruit peel-based complementary feeding (MP-ASI) formulation on total protein, albumin, and zinc levels in a malnutrition rat model. This experimental study employed a pre–posttest randomized controlled group design involving 15 male Sprague Dawley rats divided into three groups (KN, KP, and P). Malnutrition was induced using a 5% low-protein diet for 21 days, followed by intervention with the MP-ASI formula at a dose of 2.4 g/day/200 g BW. Parameters measured included weekly body weight, serum total protein, albumin, and zinc levels before and after the intervention. Data were analyzed using one-way ANOVA Tukey's post hoc test, and paired t-test. The results demonstrated marked improvements in nutritional biomarkers following the intervention, with total protein increasing from 1.13 to 6.88 g/dL, albumin from 1.53 to 4.53 g/dL, and zinc from 0.67 to 1.34 g/dL (all p = 0.001). In contrast, no significant improvement was observed in the malnutrition control group. The combination of soybean and dragon fruit peel in MP-ASI formulations has the potential to improve protein, albumin, and zinc levels under malnutrition conditions and may serve as a promising locally based nutritional intervention strategy.
Co-Authors Agatha Widiyawati Rauf Muhammad Abdul Restuti, Arisanty Nur Setia Vindi Atikatus Zuhro Yulianti, Adhiningsih Zora Olivi