Reinner Ishaq Lerrick
Department of Chemistry, Faculty of Science and Engineering, University of Nusa Cendana, Jl. Adi Sucipto, Penfui-Kupang 85118, NTT, Indonesia

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Journal : Molekul: Jurnal Ilmiah Kimia

DIRECT OXIDATION OF EUGENOL USING A PERMANGANATE Reinner Ishaq Lerrick
Molekul Vol 4, No 1 (2009)
Publisher : Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (440.106 KB) | DOI: 10.20884/1.jm.2009.4.1.62

Abstract

Direct oxidation of eugenol has been done using potassium permanganate. This research attempts to produce benzyl carboxylic acid, an important intermediate reactant for isoflavone synthesis, directly by breaking the p bond of allillic group attached to eugenol. The oxidation procedures were adopted from Wahyuningsih and Kusumaningsih anetol oxidation reactions. There were three modifications done i.e. one polar system of the oxidation environment, variation of time of reflux and temperature. Eugenol was firstly diluted in water by converting to its salt type and then oxidized using KMnO4 at 75 oC for 4 hours. The expected acid was separated by acidifying using sulfuric acid.The result showed that direct oxidation of eugenol using modified method of Wahyuningsih gave only a vicinal diol which undergoes polymerization into product in 80% yield with 83% purity. However, variation of time of reflux of Wahyuningsih method showed the same result with Kusumaningsih method as brown oily viscous liquid. The product was only 38% purity.
AKTIVITAS ANTIBAKTERI Eschericia coli PADA MINYAK ATSIRI BATANG GENOAK (Acorus calamus) ASAL PULAU TIMOR Sherlly M. F. Ledoh; Reiner I. Lerrick; Debora Ratu
Molekul Vol 8, No 1 (2013)
Publisher : Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (389.563 KB) | DOI: 10.20884/1.jm.2013.8.1.120

Abstract

Telah dilakukan uji aktivitas antibakteri Eschericia coli (E. coli) minyak batang genoak (Acorus calamus). Penelitian ini dilakukan melalui destilasi uap batang genoak yang diikuti analisis komposisi kimianya menggunakan GC-MS, dan uji antibakteri terhadap bakteri E. coli menggunakan metode hitung cawan. Hasil penelitian diperoleh minyak genoak dengan rendemen 0,17% dan asaron sebagai komponen utama minyak genoak sebesar 89,81%. Minyak genoak dapat menghambat pertumbuhan bakteri E. coli sebesar 95,76% pada kosentrasi 10% (v/v).