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All Journal Jurnal Kesehatan Gigi dan Mulut (JKGM) Sriwijaya Journal of Dentistry
Listia Eka Merdekawati
Universitas Sriwijaya
Dentistry Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health

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The Potential Antibacterial Power of Ethanol Extract of Durian Peel (Durio zibethinus murr) Against Enterococcus faecalis Aurelia Maulini Rizky; Danica Anastasia; Listia Eka Merdekawati
Sriwijaya Journal of Dentistry Vol. 1 No. 1 (2020): Sriwijaya Journal of Dentistry
Publisher : Dentistry Study Program, Faculty of Medicine Universitas Sriwijaya 

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (162.802 KB) | DOI: 10.32539/sjd.v1i1.200

Abstract

Durian (Durio zibethinus murr) is a fruit with the 4th commodity in Indonesia where the skin has antibacterial properties. Durian peel contains active substances in the form of flavonoids, alkaloids, saponins, tannins, and triterpenoids which have significant antibacterial activity against Gram-positive bacteria such as Enterococcus faecalis. This study aimed to determine the antibacterial activity of the ethanol extract of durian peel against Enterococcus faecalis bacteria. Methods: This was quasi-experimental using post-test only control group design with 4 treatment groups consisting of ethanol extract of durian peel with concentrations of 10%, 15%, 20%, 25% and 2% chlorhexidine as a control group with 6 repetitions. The antibacterial activity was tested using the agar diffusion method Kirby-Bauer discs with Mueller Hinton Agar media. All groups were assessed after 24 hours of incubation period at 37°C. The diameter of the inhibition zone was calculated using a caliper and the data were analyzed using the One Way ANOVA test and the Post Hoc Games Howel test. Results: There was a significant difference in the antibacterial activity of the ethanol extract of durian peel against Enterococcus faecalis between all groups except in the concentration groups of 25% and 20% as well as 15% and 10%. The higher concentration of extract formed a larger clear zone. Conclusion: the ethanol extract of durian peel concentrations of 25%, 20%, 15% and 10% have antibacterial power against Enterococcus faecalis bacteria with an average of 1.69 mm, 1.25 mm, 0.78 mm and 0.42 mm which are classified as weak category.
EFEKTIVITAS ANTIBAKTERI KITOSAN CANGKANG KEPITING BAKAU (SCYLLA SERRATA) TERHADAP PERTUMBUHAN STREPTOCOCCUS MUTANS DAN PORPHYROMONAS GINGIVALIS Mellani Cindera Negara; Sulistiawati .; Shafa Al-Afifah Silparensi; Muhammad Rizki Ramadhan; Trisnawaty Trisnawaty; Listia Eka Merdekawati
Jurnal Kesehatan Gigi dan Mulut (JKGM) Vol 8 No 1 (2026): Jurnal Kesehatan Gigi dan Mulut (JKGM)
Publisher : Jurusan Kesehatan Gigi, Poltekkes Kemenkes Palembang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36086/jkgm.v8i1.3836

Abstract

Streptococcus mutans and Porphyromonas gingivalis are major pathogenic bacteria involved in dental and periodontal diseases, such as caries and periodontitis. Chitosan derived from mangrove crab shells (Scylla serrata) is a natural biopolymer with potential antibacterial activity. This study aimed to evaluate the antibacterial effect of chitosan against Streptococcus mutans and Porphyromonas gingivalis based on inhibition zone diameters at concentrations of 0.25%, 0.5%, and 1%. An in vitro disk diffusion method was applied using 0.2% chlorhexidine as a positive control and distilled water as a negative control. The results showed that chitosan produced inhibition zones against both bacteria, with diameters increasing along with the concentration. The largest inhibition zone was observed at 1%, while smaller zones were formed at 0.25% and 0.5%. In conclusion, chitosan from mangrove crab shells exhibits antibacterial activity against Streptococcus mutans and Porphyromonas gingivalis, although its inhibitory effect remains lower than the positive control.
Co-Authors Aurelia Maulini Rizky Mellani Cindera Negara Muhammad Rizki Ramadhan Shafa Al-Afifah Silparensi Sulistiawati . Trisnawaty Trisnawaty