Sadagoban GK
JSS College of Pharmacy, JSS Academy of Higher Education & Research Ooty

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Empagliflozin Managed Type 2 Diabetes Mellitus in Insulin induced Hypertension: A case report Raja A; Sadagoban GK; Jemi Rachel Shaji; Renita Castelino; Swathi Swaroopa Borra
Journal of Global Pharma Technology Volume 12 Issue 12 (2020) Dec. 2020
Publisher : Journal of Global Pharma Technology

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Abstract

Insulin is an essential hormone and has been the cornerstone in the therapy of Diabetes Mellitus. This case highlights insulin-induced hypertension in a type 2 DM patient, managed adequately with empagliflozin. A 60-year female with Diabetic Nephropathy & Hypothyroidism presented with elevated blood pressure after a week of insulin administration. An elevation in the patient’s blood pressure corresponding to the administration of insulin was observed. De-challenge and re-challenge of insulin with dose adjustment, resulted in sudden spike & decrease of blood pressure, thereby pointing a suspicion towards a relation between insulin and hypertension. Discontinuation of insulin and replacement with oral hypoglycemics has resulted in controlled blood pressure levels.